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©2014 Baishideng Publishing Group Inc. All rights reserved.
World J Radiol. Dec 28, 2014; 6(12): 895-906
Published online Dec 28, 2014. doi: 10.4329/wjr.v6.i12.895
Published online Dec 28, 2014. doi: 10.4329/wjr.v6.i12.895
Functional topography of the corpus callosum investigated by DTI and fMRI
Mara Fabri, Chiara Pierpaoli, Paolo Barbaresi, Dipartimento di Medicina Sperimentale e Clinica, Sezione di Neuroscienze e Biologia Cellulare, Università Politecnica delle Marche, 60020 Ancona, Italy
Gabriele Polonara, Dipartimento di Scienze Cliniche Specialistiche e Odontostomatologiche, Sezione di Scienze Radiologiche, Università Politecnica delle Marche, 60020 Ancona, Italy
Author contributions: All authors contributed to the paper.
Supported by Ministero Istruzione, Università e Ricerca (MIUR; PRIN 2007, 2009)
Correspondence to: Mara Fabri, Professor, Dipartimento di Medicina Sperimentale e Clinica, Sezione di Neuroscienze e Biologia Cellulare, Università Politecnica delle Marche, Via Tronto 10/A, 60020 Ancona, Italy. m.fabri@univpm.it
Telephone: +39-071-2206193 Fax: +39-071-2206052
Received: May 28, 2014
Revised: October 16, 2014
Accepted: October 28, 2014
Published online: December 28, 2014
Processing time: 214 Days and 19.3 Hours
Revised: October 16, 2014
Accepted: October 28, 2014
Published online: December 28, 2014
Processing time: 214 Days and 19.3 Hours
Core Tip
Core tip: A combined approach using diffusion tensor imaging and tractography, two recently developed imaging techniques, and functional magnetic resonance imaging (fMRI) has enabled detection of fMRI activation evoked by specific sensory or motor tasks in the corpus callosum, and reconstruction of the trajectory of the commissural fibers interconnecting primary cortical areas activated by the same tasks. These findings confirm that the corpus callosum has a functional topographic organization and that fMRI may be used to explore it.