Camera L, Severino R, Faggiano A, Masone S, Mansueto G, Maurea S, Fonti R, Salvatore M. Contrast enhanced multi-detector CT and MR findings of a well-differentiated pancreatic vipoma. World J Radiol 2014; 6(10): 840-845 [PMID: 25349667 DOI: 10.4329/wjr.v6.i10.840]
Corresponding Author of This Article
Luigi Camera, MD, Department of Radiology, University “Federico II”, Via S. Pansini 5, 80131 Naples, Italy. camera@unina.it
Research Domain of This Article
Radiology, Nuclear Medicine & Medical Imaging
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Radiol. Oct 28, 2014; 6(10): 840-845 Published online Oct 28, 2014. doi: 10.4329/wjr.v6.i10.840
Contrast enhanced multi-detector CT and MR findings of a well-differentiated pancreatic vipoma
Luigi Camera, Rosa Severino, Antongiulio Faggiano, Stefania Masone, Gelsomina Mansueto, Simone Maurea, Rosa Fonti, Marco Salvatore
Luigi Camera, Rosa Severino, Simone Maurea, Marco Salvatore, Department of Advanced Biomedical Sciences, Diagnostic Imaging Section, University “Federico II”, 80131 Naples, Italy
Luigi Camera, Rosa Fonti, Institute of Biostructures and Bioimaging (C.N.R.), 80131 Naples, Italy
Antongiulio Faggiano, Department of Clinical Medicine and Surgery, Endocrinology Section, University “Federico II”, 80131 Naples, Italy
Stefania Masone, Department of Gastro-enterology, Endocrinology and Surgery, University “Federico II”, 80131 Naples, Italy
Gelsomina Mansueto, Department of Advanced Biomedical Sciences, Pathology Section University “Federico II”, 80131 Naples, Italy
Author contributions: Camera L observed the case, designed the report and revised the manuscript; Severino R drafted the manuscript; Faggiano A was the referring physician; Masone S performed the laparotomy; Mansueto G performed histo-pathological and immuno-histochemical analysis; Maurea S performed the MR study; Fonti R performed the somatostatin receptor scintigraphy; Salvatore M edited the manuscript.
Correspondence to: Luigi Camera, MD, Department of Radiology, University “Federico II”, Via S. Pansini 5, 80131 Naples, Italy. camera@unina.it
Telephone: +39-81-7463560 Fax: +39-81-5457081
Received: May 7, 2014 Revised: September 18, 2014 Accepted: September 23, 2014 Published online: October 28, 2014 Processing time: 170 Days and 13.9 Hours
Core Tip
Core tip: Pancreatic vipoma is an extremely rare tumor accounting for less than 2% of endocrine pancreatic neoplasms. While cross-sectional imaging findings are usually not specific, exact localization of the tumor by means of either computed tomography (CT) or magnetic resonance (MR) is pivotal for surgical planning. We report the case of a 70 years old female with a two years history of watery diarrhoea who was found to have a solid, inhomogeneously enhancing lesion at the level of the pancreatic tail at Gadolinium-enhanced MR. The tumor had been prospectively overlooked at a contrast-enhanced multi-detector CT but it was subsequently confirmed by somatostatin-receptor scintigraphy. The patient first underwent a successful symptomatic treatment with somatostatin analogues and was then submitted to a distal pancreasectomy with splenectomy.
