Original Article
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World J Radiol. Aug 28, 2013; 5(8): 295-303
Published online Aug 28, 2013. doi: 10.4329/wjr.v5.i8.295
Diagnostic accuracy of cardiac computed tomography angiography for myocardial infarction
Monvadi B Srichai, Hersh Chandarana, Robert Donnino, Irene Isabel P Lim, Christianne Leidecker, James Babb, Jill E Jacobs
Monvadi B Srichai, Department of Cardiology, Medstar Georgetown University Hospital, Washington, DC, 20007, United States
Hersh Chandarana, James Babb, Jill E Jacobs, Department of Radiology, New York University School of Medicine, New York, NY 10016, United States
Robert Donnino, Department of Medicine (Cardiology Division), New York University School of Medicine, New York, NY 10016, United States
Irene Isabel P Lim, Department of General Surgery, New York University School of Medicine, New York, NY 10016, United States
Christianne Leidecker, Siemens AG, Healthcare Sector, 91301 Forchheim, Germany
Author contributions: Srichai MB, Chandarana H, Jacobs JE designed the research; Srichai MB, Chandarana H, Donnino R, Lim IIP, Jacobs JE performed the research; Srichai MB and Babb J contributed statistical analyses and analyzed the data; Srichai MB wrote the paper; Srichai MB, Chandarana H, Donnino R, Leidecker C and Jacobs JE reviewed the manuscript.
Supported by Grant from the Agency for Healthcare Research and Quality, No. K12HS019473
Correspondence to: Monvadi B Srichai, MD, FAHA, FACC, Department of Cardiology, Medstar Georgetown University Hospital, 3800 Reservoir Road NW, 5 PHC, Washington, DC, 20007, United States. srichai@alum.mit.edu
Telephone: +1-202-4445515 Fax: +1-202-4445515
Received: April 26, 2013
Revised: June 13, 2013
Accepted: July 17, 2013
Published online: August 28, 2013
Processing time: 124 Days and 9.9 Hours
Core Tip

Core tip: Cardiac magnetic resonance (CMR) imaging is considered the gold standard non-invasive imaging technique for identification of myocardial infarction and viability. However, not all patients are eligible for CMR due to potential contraindications, especially in patients with electronic implants. Although electrocardiogram, nuclear imaging and echocardiography have been used to identify myocardial infarction, they generally have low sensitivity, particular for small scar regions. Cardiac computed tomography represents a viable alternative to CMR, and low voltage late enhancement cardiac computed tomography angiography imaging provides the best diagnostic accuracy compared to high and mixed voltage acquisitions for identification of myocardial infarct regions.