Review
Copyright ©2013 Baishideng Publishing Group Co., Limited. All rights reserved.
World J Radiol. Nov 28, 2013; 5(11): 398-410
Published online Nov 28, 2013. doi: 10.4329/wjr.v5.i11.398
Screening and early diagnosis of osteoporosis through X-ray and ultrasound based techniques
Paola Pisani, Maria Daniela Renna, Francesco Conversano, Ernesto Casciaro, Maurizio Muratore, Eugenio Quarta, Marco Di Paola, Sergio Casciaro
Paola Pisani, Maria Daniela Renna, Francesco Conversano, Ernesto Casciaro, Marco Di Paola, Sergio Casciaro, National Council of Research, Institute of Clinical Physiology, 73100 Lecce, Italy
Maurizio Muratore, Eugenio Quarta, O.U. of Rheumatology, “Galateo” Hospital, 73100 Lecce, Italy
Author contributions: All the authors were involved in designing the study and writing the manuscript.
Supported by Partially funded by FESR P.O. Apulia Region 2007-2013-Action 1.2.4, No. 3Q5AX31
Correspondence to: Sergio Casciaro, PhD, Eng., National Council of Research, Institute of Clinical Physiology, c/o Campus Universitario Ecotekne, via per Monteroni, 73100 Lecce, Italy. sergio.casciaro@cnr.it
Telephone: +39-0832-422310 Fax: +39-0832-422341
Received: June 28, 2013
Revised: October 2, 2013
Accepted: November 1, 2013
Published online: November 28, 2013
Processing time: 152 Days and 20 Hours
Core Tip

Core tip: Early diagnosis is the key for an appropriate osteoporosis management. To date, dual X-ray absorptiometry is the most commonly used and validated method for bone densitometry in clinical practice. Nevertheless, some important limitations like radiation dose and high costs do not allow it to be the true “gold standard technique” and make it unsuitable as a screening tool at the primary health care level for prevention purposes. As a consequence, interest in developing reliable pre-screening devices for osteoporosis assessment such as quantitative ultrasound scanners is growing up. Ultrasound-based techniques involve no radiation exposure, represent a cheap solution and they are also becoming more and more reliable for assessing bone quality.