Observational Study
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Radiol. Sep 28, 2024; 16(9): 429-438
Published online Sep 28, 2024. doi: 10.4329/wjr.v16.i9.429
Cerebral perfusion in patients with unilateral internal carotid artery occlusion by dual post-labeling delays arterial spin labeling imaging
Gui-Rong Zhang, Yan-Yan Zhang, Wen-Bin Liang, Dun Ding
Gui-Rong Zhang, Yan-Yan Zhang, Wen-Bin Liang, Dun Ding, Department of Medical Imaging, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710043, Shaanxi Province, China
Author contributions: Ding D designed the research study; Zhang YY and Liang WB analyzed the data; Zhang GR analyzed the data and wrote the manuscript. All authors have read and approve the final manuscript.
Supported by The Key Research and Development Program Projects of Shaanxi Province of China, No. S2023-YF-YBSF-0273; and Natural Science Foundation of Shaanxi Province of China, No. 2022JQ-900.
Institutional review board statement: The study was reviewed and approved by the Second Affiliated Hospital of Xi'an Jiaotong University Institutional Review Board, (Approval No. 2022156).
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: No potential conflict of interest was reported by the authors.
Data sharing statement: Technical appendix, statistical code, and dataset available from the corresponding author at hequren521@163.com. Data sharing consent was not obtained but the presented data are anonymized and risk of identification is low.
STROBE statement: The authors have read the STROBE Statement—checklist of items, and the manuscript was prepared and revised according to the STROBE Statement—checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Dun Ding, MD, PhD, Assistant Professor, Department of Medical Imaging, The Second Affiliated Hospital of Xi'an Jiaotong University, No. 157 West Fifth Road, Xi’an 710043, Shaanxi Province, China. hequren521@163.com
Received: July 12, 2024
Revised: August 29, 2024
Accepted: September 6, 2024
Published online: September 28, 2024
Processing time: 76 Days and 14.9 Hours
Core Tip

Core Tip: In this study, the dual post-labeling delays (PLD) arterial spin labeling (ASL) technique was used for cerebral blood flow (CBF) imaging in unilateral internal carotid artery occlusion (ICAO) patients. Intelligent ASL analysis software was used for rapid quantification of regional CBF, including the Alberta Stroke Program Early Computed Tomography Score (ASPECTS) regions. A comparison with the controls suggests that unilateral ICAO resulted in hypoperfusion in the global and middle cerebral artery territory, affecting most of the ASPECTS area on the occluded side and a small part of the ASPECTS area on the nonoccluded side. The dual PLD settings are more suitable for accurate CBF quantification in ICAO.