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Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Radiol. Jun 28, 2024; 16(6): 139-167
Published online Jun 28, 2024. doi: 10.4329/wjr.v16.i6.139
Imaging features and management of focal liver lesions
Gökhan Kahraman, Kemal Murat Haberal, Osman Nuri Dilek
Gökhan Kahraman, Department of Radiology, Suluova State Hospital, Amasya 05500, Türkiye
Kemal Murat Haberal, Department of Radiology, Başkent University Faculty of Medicine, Ankara 06490, Türkiye
Osman Nuri Dilek, Department of Surgery, İzmir Katip Celebi University, School of Medicine, İzmir 35150, Türkiye
Author contributions: Kahraman G wrote the paper; Haberal KM collected and reported the patients’ data and images; Dilek ON revised the article critically for scientific content.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: Https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Gökhan Kahraman, MD, Chief, Department of Radiology, Suluova State Hospital, Maarif, Yunus Emre St No. 1, Amasya 05500, Türkiye.gokhankahraman1@outlook.com
Received: March 11, 2024
Revised: April 28, 2024
Accepted: May 22, 2024
Published online: June 28, 2024
Processing time: 107 Days and 4.6 Hours
Core Tip

Core Tip: The incidence of incidentally detected focal liver lesions (FLL) has risen significantly due to increased radiological imaging use. While benign FLLs are more common, even in patients with primary malignancy, accurate diagnosis is clinically significant. Non-invasive evaluation, such as ultrasound, computed tomography, and magnetic resonance imaging (MRI), is common in clinical practice. MRI, particularly with hepatobiliary-specific contrast agents, has enhanced FLL characterization, reducing unnecessary biopsies. Guidelines from the American College of Radiology, American College of Gastroenterology, and American Association for the Study of Liver Diseases offer evidence-based recommendations for optimal imaging and management. This article provides a comprehensive review of FLL, covering imaging methods, current techniques and modalities, innovations in imaging, contrast agents, features of nonmetastatic benign and malignant FLLs, and current management recommendations.