Retrospective Study
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Radiol. Nov 28, 2024; 16(11): 644-656
Published online Nov 28, 2024. doi: 10.4329/wjr.v16.i11.644
Pancreatic volume change using three dimensional-computed tomography volumetry and its relationships with diabetes on long-term follow-up in autoimmune pancreatitis
Ryuichi Shimada, Yasunari Yamada, Kazuhisa Okamoto, Kazunari Murakami, Mitsuteru Motomura, Hajime Takaki, Kengo Fukuzawa, Yoshiki Asayama
Ryuichi Shimada, Yoshiki Asayama, Department of Radiology, Oita University Faculty of Medicine, Yufu 879-5593, Oita, Japan
Yasunari Yamada, Hajime Takaki, Department of Radiology, Oita Red Cross Hospital, Oita 870-0033, Oita, Japan
Kazuhisa Okamoto, Kazunari Murakami, Department of Gastroenterology, Oita University Faculty of Medicine, Yufu 879-5593, Oita, Japan
Mitsuteru Motomura, Department of Hepato-Biliary-Pancreatic Internal Medicine, Oita Red Cross Hospital, Oita 870-0033, Oita, Japan
Kengo Fukuzawa, Department of Surgery, Oita Red Cross Hospital, Oita 870-0033, Oita, Japan
Author contributions: Shimada R and Yamada Y designed and conducted the study; Shimada R wrote the paper; Yamada Y contributed to the analysis; Okamoto K and Motomura M provided clinical advice; Asayama Y, Murakami K, Fukuzawa K, and Takaki H supervised the study.
Institutional review board statement: The study was approved by the institutional review board in Oita University Faculty of Medicine and Oita Red Cross Hospital.
Informed consent statement: Patients were not required to give informed consent to the study because the analysis used anonymized clinical data that were obtained after each patient agreed to treatment by written consent.
Conflict-of-interest statement: The authors report no relevant conflicts of interest for this article.
Data sharing statement: The data used to support the findings to this study are available from the corresponding author upon request.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ryuichi Shimada, MD, Assistant Professor, Department of Radiology, Oita University Faculty of Medicine, Yufu city, Hasamamachi, Idaigaoka1-1, Yufu 879-5593, Oita, Japan. rshimada@oita-u.ac.jp
Received: July 25, 2024
Revised: September 7, 2024
Accepted: September 23, 2024
Published online: November 28, 2024
Processing time: 124 Days and 20.3 Hours
Core Tip

Core Tip: To the best of our knowledge, no previous studies have reported on pancreatic volume (PV) changes during long-term follow-up in patients with autoimmune pancreatitis (AIP). In this study, we investigated PV changes using computed tomography volumetry and examined their relationships with IgG4 and diabetes in patients with AIP with long-term follow-up. PV reduced exponentially and rapidly during the first 25 months and then more slowly. IgG4 levels were positively correlated with PV during long-term follow-up in most patients. Pancreatic atrophy occurred during long-term follow-up in all patients, and is considered an important factor associated with diabetes.