Prospective Study
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Radiol. Feb 28, 2023; 15(2): 32-41
Published online Feb 28, 2023. doi: 10.4329/wjr.v15.i2.32
Effects of combining multiple dose reduction techniques on coronary computed tomography angiography
Xiao-Lu Hu, Pei-Kai Huang, Meng Zhang, Jun Chen, Meng-Qiang Xiao
Xiao-Lu Hu, Pei-Kai Huang, Meng Zhang, Jun Chen, Meng-Qiang Xiao, Department of Imaging, Zhuhai Hospital, Guangdong Provincial Hospital of Traditional Chinese Medicine, Zhuhai 650031, Guangdong Province, China
Author contributions: Hu XL and Huang PK were involved in drafting the manuscript; Zhang M and Huang PK were involved in acquisition of data; Chen J prepared the figures; Xiao MQ reviewed and revised the manuscript; All authors have read and approved the final manuscript.
Supported by Zhuhai Medical Research Fund, No. ZH3310200001PJL.
Institutional review board statement: This study was approved by the institutional review board of Guangdong Provincial Hospital of Traditional Chinese Medicine, No. BF2020-229-01.
Informed consent statement: All patients provided written consent, and written informed consent was obtained from each patient or the patient’s family before performing the computed tomography scan. This study was conducted in accordance with the Declaration of Helsinki.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: The datasets used or analyzed during the current study are available from the corresponding author on reasonable request.
CONSORT 2010 statement: The authors have read the CONSORT 2010 Statement, and the manuscript was prepared and revised according to the CONSORT 2010 Statement.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Meng-Qiang Xiao, Doctor, Deputy Doctor, Department of Imaging, Zhuhai Hospital, Guangdong Provincial Hospital of Traditional Chinese Medicine, No. 53 Jingle Road, Zhuhai 650031, Guangdong Province, China. xmqzhuhai@163.com
Received: May 29, 2022
Peer-review started: May 29, 2022
First decision: August 22, 2022
Revised: September 23, 2022
Accepted: February 13, 2023
Article in press: February 13, 2023
Published online: February 28, 2023
Processing time: 270 Days and 6.3 Hours
Core Tip

Core Tip: Coronary computed tomography angiography (CCTA) is the preferred non-invasive examination method for coronary heart disease (CHD). The present study was the first to combine multiple dose reduction techniques, including narrow acquisition window, low tube voltage, lower tube current, and isocentric scanning, to decrease CCTA radiation exposure of patients with suspected CHD. The radiation dose for the group with multiple dose reduction was approximately 33.63% (1.13 ± 0.35/3.36 ± 1.30) of the dose associated with the conventional method.