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World J Radiol. Jul 28, 2022; 14(7): 219-228
Published online Jul 28, 2022. doi: 10.4329/wjr.v14.i7.219
Impact of X-radiation in the management of COVID-19 disease
Aishwarya T A, Divya K Mohan, K Nandhini, Venkateswarlu Raavi, Venkatachalam Perumal
Aishwarya T A, Divya K Mohan, K Nandhini, Venkatachalam Perumal, Department of Human Genetics, Sri Ramachandra Institute of Higher Education and Research (Deemed to be University), Porur, Chennai 600 116, Tamil Nadu, India
Venkateswarlu Raavi, Department of Cell Biology and Molecular Genetics, Sri Devaraj Urs Academy of Higher Education and Research (Deemed to be University), Tamaka, Kolar 563 103, Karnataka, India
Author contributions: Aishwarya T A, Mohan DK, Nandhini K contributed to review of literature and preparation of the draft; Raavi V contributed to conceptualization and design of the work, revision, and editing; Perumal V contributed to conceptualization and approval of the final version of the manuscript.
Conflict-of-interest statement: All the authors declared that there is no conflict of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non-Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Venkatachalam Perumal, DSc, PhD, Professor, Department of Human Genetics, Sri Ramachandra Institute of Higher Education and Research (Deemed to be University), Porur, Chennai 600116, Tamil Nadu, India. venkip@yahoo.com
Received: March 27, 2022
Peer-review started: March 27, 2022
First decision: June 8, 2022
Revised: June 16, 2022
Accepted: July 18, 2022
Article in press: July 18, 2022
Published online: July 28, 2022
Processing time: 122 Days and 2.4 Hours
Core Tip

Core Tip: Majority of asymptomatic individuals with coronavirus disease 2019 (COVID-19) disease, an early diagnosis was a challenge despite the gold standard reverse-transcription polymerase chain reaction measures the viral nucleic acid with a turnaround period of reporting for 5-6 h. This ultimately led to the usage of chest-X radiography with sensitivity up to 80%, which served as a screening tool for COVID-19. X-radiation-based computed tomography imaging served as another modality to monitor the severity of COVID-19 disease with sensitivity up to 98%. Low-dose radiation therapy with a limited setting showed that it can complement drug therapies in the management of COVID-19. Therefore, X-rays on a whole are been widely used for both diagnostic and therapeutic management of COVID-19 disease.