Prospective Study
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Radiol. Oct 28, 2021; 13(10): 344-353
Published online Oct 28, 2021. doi: 10.4329/wjr.v13.i10.344
Shoulder adhesive capsulitis in cancer patients undergoing positron emission tomography - computed tomography and the association with shoulder pain
Daichi Hayashi, Elaine Gould, Robert Shroyer, Eric van Staalduinen, Jie Yang, Musa Mufti, Mingqian Huang
Daichi Hayashi, Elaine Gould, Robert Shroyer, Eric van Staalduinen, Musa Mufti, Mingqian Huang, Department of Radiology, State University of New York at Stony Brook, Stony Brook, NY 11794, United States
Jie Yang, Department of Family, Population and Preventive Medicine, Stony Brook Medicine, Stony Brook, NY 11794, United States
Author contributions: Hayashi D, Gould E and Huang M designed the research study; Hayashi D, Gould E, Shroyer R, van Staalduinen E, Mufti M and Huang M performed the research including data collection and electronic medical record review; Gould E, Shroyer R and Huang M interpreted positron emission tomography - computed tomography images; Yang J performed the statistical analyses; Hayashi D analyzed results and wrote the manuscript; all authors have read, edited and approved the final manuscript.
Institutional review board statement: Our prospective study received Institutional Review Board approval at our institution (Protocol# 2015-3396-R2).
Clinical trial registration statement: Our study is not a clinical trial. Therefore, there is no Clinical Trial Registration Statement applicable to this submission.
Informed consent statement: Written informed consent was obtained from all patients.
Conflict-of-interest statement: All authors have nothing to disclose.
Data sharing statement: Patient data are not available for sharing for protection of patient confidentiality and anonymity. No additional data are available.
CONSORT 2010 statement: The authors have read the STROBE Statement—checklist of items, and the manuscript was prepared and revised according to the STROBE Statement—checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Daichi Hayashi, MD, PhD, Associate Professor, Department of Radiology, State University of New York at Stony Brook, HSC Level 4, Room 120, Stony Brook, NY 11794, United States. daichi.hayashi@stonybrookmedicine.edu
Received: March 13, 2021
Peer-review started: March 13, 2021
First decision: July 31, 2021
Revised: August 3, 2021
Accepted: September 14, 2021
Article in press: September 14, 2021
Published online: October 28, 2021
Processing time: 226 Days and 21.7 Hours
Core Tip

Core Tip: Adhesive capsulitis is a relatively common condition that can develop in cancer patients during treatment. However, there has been relatively scant literature evidence on Positron emission tomography - computed tomography (PET-CT) findings specific to adhesive capsulitis. Our study showed that, in symptomatic cancer patients, metabolic activities in the rotator interval were higher than asymptomatic patients overall, and also specifically for lung cancer patients. Presence of adhesive capsulitis may explain shoulder pain or stiffness in cancer patients, which can be incidentally diagnosed on PET-CT. Demographic characteristics, treatment regimen, and cancer type did not appear to be an independent risk factor.