Case Report
Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Radiol. Mar 28, 2015; 7(3): 61-65
Published online Mar 28, 2015. doi: 10.4329/wjr.v7.i3.61
Transarterial chemoembolization for liver metastases from solid pseudopapillary epithelial neoplasm of pancreas: A case report
TV Prasad, KS Madhusudhan, Deep N Srivastava, Nihar R Dash, Arun K Gupta
TV Prasad, KS Madhusudhan, Deep N Srivastava, Arun K Gupta, Department of Radiology, All India Institute of Medical Sciences, New Delhi 110029, India
Nihar R Dash, Department of Gastrointestinal Surgery, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India
Author contributions: All authors contributed to this manuscript.
Ethics approval: The study was reviewed and approved.
Informed consent: This is to state that all the details revealing the identity of the patient are omitted from the manuscript. Informed consent was waived off because of the retrospective nature of the case report.
Conflict-of-interest: None.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Dr. KS Madhusudhan, MD, Department of Radiology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India. drmadhuks@gmail.com
Telephone: +91-98-68398826 Fax: +91-11-26588663
Received: November 15, 2014
Peer-review started: November 16, 2014
First decision: December 26, 2014
Revised: January 23, 2015
Accepted: February 10, 2015
Article in press: February 12, 2015
Published online: March 28, 2015
Processing time: 129 Days and 16.2 Hours
Abstract

Solid pseudo-papillary epithelial neoplasm (SPEN) is a rare epithelial tumor of pancreas with a low malignant potential occurs most commonly in young females. We report a case of 40 years old woman presented with extensive liver metastasis from SPEN of pancreatic body for which she was operated four years ago. Due to the extensive nature of metastatic disease she was offered Transarterial chemoembolisation (TACE) using gemcitabine as chemotherapeutic agent. Short term follow up after a month of TACE with multiphase computed tomography showed > 90% resolution in the viable tumor with significant clinical improvement. TACE ensures targeted delivery of chemotherapeutic drugs in higher doses with least systemic toxicity and is more effective and safe than systemic chemotherapy. TACE with gemcitabine was found to be very effective in our patient with numerous liver metastasis.

Keywords: Solid pseudopapillary epithelial neoplasm; Liver metastases; Transarterial chemoembolization; Gemcitabine

Core tip: Solid pseudo-papillary epithelial neoplasm (SPEN) is a rare epithelial tumor of pancreas which is generally less aggressive and patients rarely present with liver metastasis. Our patient is a middle aged lady presented with extensive liver metastasis several years after the removal of primary tumor. Transarterial chemoembolisation (TACE) is a recognized treatment modality for inoperable hepatocellular carcinoma and metastasis from certain tumors. However, this novel technique is reported to be used only once for a patient with SPEN metastasis. In our patient, we performed TACE with gemcitabine as chemotherapeutic agent with encouraging short term results.