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World J Radiol. Mar 28, 2013; 5(3): 98-105
Published online Mar 28, 2013. doi: 10.4329/wjr.v5.i3.98
Imaging of pancreatic ductal adenocarcinoma: State of the art
Eric Peter Tamm, Priya Ranjit Bhosale, Raghu Vikram, Leonardo Pimentel de Almeida Marcal, Aparna Balachandran
Eric Peter Tamm, Priya Ranjit Bhosale, Raghu Vikram, Leonardo Pimentel de Almeida Marcal, Aparna Balachandran, Department of Diagnostic Radiology, Division of Diagnostic Imaging, University of Texas, MD Anderson Cancer Center, Houston, TX 77230-1402, United States
Author contributions: Tamm EP wrote the paper; Bhosale PR, Vikram R, de Almeida Maracle LP and Balachandran A contributed to editing paper, contribution of ideas and topics, and contribution of cases to illustrate.
Correspondence to: Eric Peter Tamm, MD, Department of Diagnostic Radiology, Division of Diagnostic Imaging, University of Texas, MD Anderson Cancer Center, PO Box 301402, Houston, TX 77230-1402, United States. etamm@mdanderson.org
Telephone: +1-713-7453231 Fax: +1-713-7451302
Received: June 4, 2012
Revised: September 22, 2012
Accepted: September 29, 2012
Published online: March 28, 2013
Abstract

Significant advances in imaging technology have changed the management of pancreatic cancer. In computed tomography (CT), this has included development of multidetector row, rapid, thin-section imaging that has also facilitated the advent of advanced reconstructions, which in turn has offered new perspectives from which to evaluate this disease. In magnetic resonance imaging, advances including higher field strengths, thin-section volumetric acquisitions, diffusion weighted imaging, and liver specific contrast agents have also resulted in new tools for diagnosis and staging. Endoscopic ultrasound has resulted in the ability to provide high-resolution imaging rivaling intraoperative ultrasound, along with the ability to biopsy via real time imaging suspected pancreatic lesions. Positron emission tomography with CT, while still evolving in its role, provides whole body staging as well as the unique imaging characteristic of metabolic activity to aid disease management. This article will review these modalities in the diagnosis and staging of pancreatic cancer.

Keywords: Pancreatic ductal adenocarcinoma; Positron emission tomography with computed tomography; Endoscopic ultrasound; Multidetector row computed tomography; Magnetic resonance imaging; Diffusion