Olivares-Antúnez Y, Dávila-Zablah YJ, Vázquez-Ávila JR, Gómez-Macías GS, Mireles-Aguilar MT, Garza-Montemayor ML. Ductal carcinoma in situ within a fibroadenoma: A case report and review of literature. World J Radiol 2024; 16(3): 58-68 [PMID: 38596169 DOI: 10.4329/wjr.v16.i3.58]
Corresponding Author of This Article
Yazmin Olivares-Antúnez, MD, Staff Physician, Department of Diagnostic Breast Imaging Center, Hospital Zambrano Hellion, Tecnológico de Monterrey, Av. Batallón de San Patricio 112, Real San Agustín, San Pedro Garza García, Nuevo León 66260, Mexico. olivaresyazmin@gmail.com
Research Domain of This Article
Radiology, Nuclear Medicine & Medical Imaging
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Radiol. Mar 28, 2024; 16(3): 58-68 Published online Mar 28, 2024. doi: 10.4329/wjr.v16.i3.58
Ductal carcinoma in situ within a fibroadenoma: A case report and review of literature
Yazmin Olivares-Antúnez, Yesika Janett Dávila-Zablah, José Raúl Vázquez-Ávila, Gabriela Sofía Gómez-Macías, María Teresa Mireles-Aguilar, Margarita Lilia Garza-Montemayor
Yazmin Olivares-Antúnez, Yesika Janett Dávila-Zablah, Margarita Lilia Garza-Montemayor, Department of Diagnostic Breast Imaging Center, Hospital Zambrano Hellion, Tecnológico de Monterrey, Nuevo León 66260, Mexico
José Raúl Vázquez-Ávila, Gabriela Sofía Gómez-Macías, Department of Patology Service, Hospital San José, Tecnológico de Monterrey, Nuevo León 64710, Mexico
Gabriela Sofía Gómez-Macías, Department of Faculty of Medicine, Hospital Universitario de la UANL, Nuevo León 64710, Mexico.
María Teresa Mireles-Aguilar, Department of Breast Surgery Center, Hospital Zambrano Hellion, Tecnológico de Monterrey, Nuevo León 66260, Mexico
Author contributions: Olivares-Antúnez Y performed searched the literature and wrote the manuscript; Dávila-Zablah YJ performed the research and reviewed the manuscript; Vázquez-Ávila JR and Gómez-Macías GS performed the subtraction image processing, discussed the results and contributed to the final manuscript; Mireles-Aguilar MT was the primary surgeon, and provided surgical insights into the case; and Garza-Montemayor ML was the senior author who supervised and made substantial contributions to the conception of the work.
Informed consent statement: Informed written consent was obtained from the patient for the publication of this report and any accompanying images.
Conflict-of-interest statement: All the authors report no conflicts of interest for this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yazmin Olivares-Antúnez, MD, Staff Physician, Department of Diagnostic Breast Imaging Center, Hospital Zambrano Hellion, Tecnológico de Monterrey, Av. Batallón de San Patricio 112, Real San Agustín, San Pedro Garza García, Nuevo León 66260, Mexico. olivaresyazmin@gmail.com
Received: December 10, 2023 Peer-review started: December 10, 2023 First decision: January 6, 2024 Revised: January 20, 2024 Accepted: March 6, 2024 Article in press: March 6, 2024 Published online: March 28, 2024 Processing time: 106 Days and 23.3 Hours
Abstract
BACKGROUND
Fibroadenoma (FA) is the most common tumor found in young women, although it can occur in any age group. Ductal carcinoma in situ (DCIS) that is confined in a FA is rare; it is most frequently reported as an incidental finding.
CASE SUMMARY
We report a case of DCIS within a FA in a 46-year-old female without cancer-related personal and family histories. The patient was diagnosed with a breast conglomerate of nodules and was followed for 1 year. In the current control image study, we found suspicious microcalcification, as a new finding, within one of the nodules. Consequently, a core biopsy of the tumor, which appeared hypoechoic, oval, and circumscribed, was performed. The pathological diagnosis was ductal carcinoma in situ within a fibroepithelial lesion. The patient underwent breast-conserving surgery and received radiotherapy as well as endocrine therapy (tamoxifen).
CONCLUSION
We recommend a multidisciplinary approach for adequate treatment and follow-up.
Core Tip: Fibroadenoma (FA) is the most common tumor found in women. Although it can occur in any age group, is important to consider when to suspicious a malignant change of FA. The case we report is of great interest to the radiology community because ductal carcinoma in situ within a FA is a challenge to diagnosis. The aim of this case report is to present the current findings in imaging studies for an early diagnosis and to not delay the treatment.
