Retrospective Study
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Radiol. Nov 28, 2024; 16(11): 638-643
Published online Nov 28, 2024. doi: 10.4329/wjr.v16.i11.638
Spectra of intracranial diseases in Chinese military pilots (cadets) unqualified for transfer to pilot modified high performance aircraft
Yao Zhao, Di Gao, Yan-Bing Liu, Jing-Jing Xue, Xiang Lu, Jing-Jing Dong, Yan Zhang, Jia Zeng
Yao Zhao, Di Gao, Yan-Bing Liu, Jing-Jing Xue, Xiang Lu, Jing-Jing Dong, Yan Zhang, Jia Zeng, Naval Medical Center, Naval Medical University of Chinese PLA, Shanghai 200052, China
Co-first authors: Yao Zhao and Di Gao.
Author contributions: Zhao Y, Gao D and Liu YB contributed equally to this work, developed the methodology, collected data, analyzed and interpreted data, written manuscript; Xue JJ, Lu X and Dong JJ collected and analyzed the clinical data; Xue JJ, Gao D and Zhang Y wrote the manuscript; Zeng J revised the manuscript and designed the research; all of the authors read and approved the final version of the manuscript to be published.
Supported by The Key Projects of Medical Service Scientific Research of the Navy Medical Center, China, No. 20M2302.
Institutional review board statement: Institutional Review Board declares support for the research of this project.
Informed consent statement: All enrolled cases have signed the informed consent form.
Conflict-of-interest statement: All authors declare no conflict of interest in publishing the manuscript.
Data sharing statement: All authors agree to the sharing of relevant clinical data. Please contact the corresponding author for details.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jia Zeng, BMed, Associate Chief Physician, Naval Medical Center, Naval Medical University of Chinese PLA, No. 338 Huaihaixi Road, Changning District, Shanghai 200052, China. zengjia411@163.com
Received: August 26, 2024
Revised: September 19, 2024
Accepted: September 26, 2024
Published online: November 28, 2024
Processing time: 93 Days and 1 Hours
Abstract
BACKGROUND

With very high mortality and disability rates, cerebrovascular diseases and intracranial tumors severely threaten the health and fighting strength of flying personnel, requiring great concern and intensive screening in clinic, early warning in an early and accurate manner and early intervention of diseases possibly resulting in inflight incapacitation are key emphases of aeromedical support in clinic.

AIM

To probe into the spectra of intracranial diseases, flight factors and medical imaging characteristics of military pilots (cadets) in the physical examination for transfer to pilot modified high performance aircraft, thus rendering theoretical references for clinical aeromedical support of pilots.

METHODS

A total of 554 military pilots (cadets) undergoing physical examination for transfer to pilot modified high performance aircraft from December 2020 to April 2024 in a military medical center were enrolled in this study. Then, a retrospective study was carried out on intracranial disease spectra and head magnetic resonance imaging (MRI) data of 36 pilots (cadets) who were unqualified for transfer to pilot modified high performance aircraft. Besides, a descriptive statistical analysis was conducted on the clinical data, age, fighter type and head MRI data of such pilots (cadets).

RESULTS

Abnormal head images were found in 36 out of 554 pilots (cadets) participating in the physical examination for transfer to pilot modified high performance aircraft, including arachnoid cyst in 17 (3.1%) military pilots (cadets), suspected very small aneurysm in 11 (2.0%), cavernous hemangioma in 4 (0.7%), vascular malformation in 2 (0.4%), and pituitary tumor in 3 (0.5%, one of which developed cavernous hemangioma simultaneously). Among the 17 pilots (cadets) with arachnoid cyst, 4 were identified as unqualified for transfer to pilot modified high performance aircraft because the marginal brain tissues were compressed by the cyst > 6 cm in length and diameter. The 11 pilots (cadets) with suspected very small aneurysms identified by 3.0T MRI consisted of 6 diagnosed with conus arteriosus by digital subtraction angiography and qualified for transfer to pilot modified high performance aircraft, and 5 identified as very small intracranial aneurysms with diameter < 3 mm and unqualified for transfer to pilot modified high performance aircraft. No symptoms and signs were observed in the 4 military pilots (cadets) with cavernous hemangioma, and the results of MRI revealed bleeding. The 1 of the 4 had the lesion located in pons and developed Rathke cyst in pituitary gland at the same time, and unqualified for transfer to pilot modified high performance aircraft. The 2 of the 4 were unqualified for flying, and 2 transferred to air combat service division. The 2 pilots (cadets) with vascular malformation were identified as unqualified for transfer to pilot modified high performance aircraft. Among the 3 pilots (cadets) with pituitary tumor, one pilot cadet was identified as unqualified for flying since the tumor compressed the optic chiasma, one had cavernous hemangioma in pons in the meantime and transferred to air combat service division, and one was diagnosed with nonfunctional microadenoma and qualified for transfer to pilot modified high performance aircraft.

CONCLUSION

High-resolution head MRI examination is of great significance for screening and detecting cerebrovascular diseases and intracranial tumors in military flying personnel, and attention should be paid to its clinical application to physical examination for transfer to pilot modified high performance aircraft.

Keywords: Aircrew; Cranial magnetic resonance imaging; Cerebrovascular diseases; Intracranial tumors; Aeromedical appraisal

Core Tip: Cerebrovascular diseases and intracranial tumors may lead to intracranial hemorrhage, epilepsy, headache, neurological impairment and other risk factors for inflight incapacitation. High-resolution head magnetic resonance imaging examination is of great significance for screening and detecting cerebrovascular diseases and intracranial tumors in military flying personnel, and its clinical application to physical examination for transfer to pilot modified high performance aircraft should be attached with great importance. It is essential to detect and to intervene and treat cerebrovascular diseases and intracranial tumors as early as possible, thus reducing the grounding rate and maintaining flight safety.