Yang M, Pu SL, Li L, Ma Y, Qin Q, Wang YX, Huang WL, Hu HY, Zhu MF, Li CZ. Hypoparathyroidism with situs inversus totalis: A case report. World J Radiol 2024; 16(10): 561-568 [DOI: 10.4329/wjr.v16.i10.561]
Corresponding Author of This Article
Sheng-Lan Pu, Doctor, MD, PhD, Associate Chief Physician, Associate Professor, Deputy Director, Department of General Medicine, First People’s Hospital of Zunyi (Third Affiliated Hospital of Zunyi Medical University), No. 98 Fenghuang Road, Huichuan District, Zunyi 563000, Guizhou Province, China. 18685227587@163.com
Research Domain of This Article
Multidisciplinary Sciences
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Radiol. Oct 28, 2024; 16(10): 561-568 Published online Oct 28, 2024. doi: 10.4329/wjr.v16.i10.561
Hypoparathyroidism with situs inversus totalis: A case report
Mao Yang, Sheng-Lan Pu, Ling Li, Yu Ma, Qin Qin, Yan-Xia Wang, Wen-Long Huang, Hong-Ya Hu, Mei-Feng Zhu, Chun-Zhu Li
Mao Yang, Sheng-Lan Pu, Ling Li, Qin Qin, Yan-Xia Wang, Wen-Long Huang, Hong-Ya Hu, Mei-Feng Zhu, Chun-Zhu Li, Department of General Medicine, First People’s Hospital of Zunyi (Third Affiliated Hospital of Zunyi Medical University), Zunyi 563000, Guizhou Province, China
Yu Ma, Department of Nutrition, First People’s Hospital of Zunyi (Third Affiliated Hospital of Zunyi Medical University), Zunyi 563000, Guizhou Province, China
Author contributions: Yang M contributed to conceptualization, manuscript writing, and editing; Pu SL contributed to conceptualization and supervision; Li L, Qin Q and Ma Y contributed to editing; Wang YX, Huang WL and Hu HY contributed to data collection; Zhu MF and Li CZ contributed to the literature review. All authors have read and approved the final manuscript.
Supported byZunyi Science and Technology Plan Program No. HZ (2022) 48; and Zunyi Science and Technology Plan Program, No. HZ (2023) 60.
Informed consent statement: Written informed consent was obtained from the patient for the publication of this report and any accompanying images.
Conflict-of-interest statement: The authors have no conflict of interest to declare.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to this checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Sheng-Lan Pu, Doctor, MD, PhD, Associate Chief Physician, Associate Professor, Deputy Director, Department of General Medicine, First People’s Hospital of Zunyi (Third Affiliated Hospital of Zunyi Medical University), No. 98 Fenghuang Road, Huichuan District, Zunyi 563000, Guizhou Province, China. 18685227587@163.com
Received: May 5, 2024 Revised: August 31, 2024 Accepted: September 19, 2024 Published online: October 28, 2024 Processing time: 175 Days and 17.5 Hours
Abstract
BACKGROUND
Hypoparathyroidism (HP) is a rare endocrine disorder, while situs inversus totalis (SIT) is a rare condition in which the internal organs are positioned in a mirrored pattern compared to their usual positions. This case illustrates some potential shared mechanisms between HP and SIT, highlighting the importance of accurate identification and prompt first emergency, offering insights for future research.
CASE SUMMARY
This report discusses a case of a middle-aged patient with adolescent-onset HP with concurrent SIT. The patient experienced recurrent episodes of increased neuromuscular excitability (manifesting as spasms in the hands and feet and laryngospasms) and even periods of unconsciousness. Initially, these symptoms led to a misdiagnosis of epilepsy. Nevertheless, upon thorough examination and treatment in the general medicine ward, the correct diagnosis was established. Corresponding treatment resulted in improved management of the patient’s symptoms.
CONCLUSION
Co-occurrence of HP and SIT may be associated with genetic mutations, chromosomal anomalies, or hereditary factors, as may other similar conditions.
Core Tip: We report a case of patient misdiagnosed with “epilepsy”, who responded well to calcium gluconate. Upon admission, the patient exhibited altered consciousness, which was initially attributed to epilepsy. However, subsequent tests identified situs inversus totalis (SIT). Despite achieving stabilization, recurring hand muscle spasms persisted. The diagnosis was revised to hypoparathyroidism with SIT and was managed via supplementation with calcium and vitamin D. Effective symptom control was noted at the nine-month follow-up.
