Published online Sep 28, 2023. doi: 10.4329/wjr.v15.i9.274
Peer-review started: June 30, 2023
First decision: August 24, 2023
Revised: September 4, 2023
Accepted: September 22, 2023
Article in press: September 22, 2023
Published online: September 28, 2023
Processing time: 88 Days and 17.8 Hours
Primary central nervous system lymphoma (PCNSL) is a rare malignant tumor originating from the lymphatic hematopoietic system. It exhibits unique imaging manifestations due to its biological characteristics.
Magnetic resonance imaging (MRI) with diffusion-weighted imaging (DWI), perfusion-weighted imaging (PWI), and magnetic resonance spectroscopy was performed. The imaging findings showed multiple space-occupying lesions with low signal on T1-weighted imaging, uniform high signal on T2-weighted imaging, and obvious enhancement on contrast-enhanced scans. DWI revealed diffusion restriction, PWI demonstrated hypoperfusion, and spectroscopy showed elevated choline peak and decreased N-acetylaspartic acid. The patient's condition significantly improved after hormone shock therapy.
This case highlights the distinctive imaging features of PCNSL and their importance in accurate diagnosis and management.
Core Tip: Primary central nervous system lymphoma (PCNSL) is a rare tumor of the central nervous system with distinctive imaging features. This case report highlights the imaging manifestations of multiple PCNSL lesions using diffusion-weighted imaging, perfusion-weighted imaging, and magnetic resonance imaging. Accurate diagnosis is crucial for appropriate management. Further research and larger studies are needed to enhance the understanding and diagnostic accuracy of PCNSL.