Lacharie M, Villa A, Milidonis X, Hasaneen H, Chiribiri A, Benedetti G. Role of pulmonary perfusion magnetic resonance imaging for the diagnosis of pulmonary hypertension: A review. World J Radiol 2023; 15(9): 256-273 [PMID: 37823020 DOI: 10.4329/wjr.v15.i9.256]
Corresponding Author of This Article
Miriam Lacharie, MSc, Researcher, Oxford Centre of Magnetic Resonance Imaging, University of Oxford, John Radcliffe Hospital, Headington, Oxford OX3 9DU, Oxford OX3 9DU, United Kingdom. miriam.lacharie@cardiov.ox.ac.uk
Research Domain of This Article
Radiology, Nuclear Medicine & Medical Imaging
Article-Type of This Article
Review
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Miriam Lacharie, Oxford Centre of Magnetic Resonance Imaging, University of Oxford, Oxford OX3 9DU, United Kingdom
Adriana Villa, Department of Diagnostic and Interventional Radiology, German Oncology Centre, Limassol 4108, Cyprus
Xenios Milidonis, Deep Camera MRG, CYENS Centre of Excellence, Nicosia, Cyprus, Nicosia 1016, Cyprus
Hadeer Hasaneen, School of Biomedical Engineering & Imaging Sciences, King's College London, London WC2R 2LS, United Kingdom
Amedeo Chiribiri, School of Biomedical Engineering and Imaging Sciences, Kings Coll London, Div Imaging Sci, St Thomas Hospital, London WC2R 2LS, United Kingdom
Giulia Benedetti, Department of Cardiovascular Imaging and Biomedical Engineering, King’s College London, London WC2R 2LS, United Kingdom
Author contributions: Villa ADM was responsible for the review concept; Lacharie M drafted the manuscript; Lacharie M provided critical revision of the manuscript for important intellectual content; and all authors critically reviewed the content.
Conflict-of-interest statement: Authors declare no conflict of interest for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Miriam Lacharie, MSc, Researcher, Oxford Centre of Magnetic Resonance Imaging, University of Oxford, John Radcliffe Hospital, Headington, Oxford OX3 9DU, Oxford OX3 9DU, United Kingdom. miriam.lacharie@cardiov.ox.ac.uk
Received: July 27, 2023 Peer-review started: July 27, 2023 First decision: September 4, 2023 Revised: September 16, 2023 Accepted: September 22, 2023 Article in press: September 22, 2023 Published online: September 28, 2023 Processing time: 61 Days and 16.5 Hours
Abstract
Among five types of pulmonary hypertension, chronic thromboembolic pulmonary hypertension (CTEPH) is the only curable form, but prompt and accurate diagnosis can be challenging. Computed tomography and nuclear medicine-based techniques are standard imaging modalities to non-invasively diagnose CTEPH, however these are limited by radiation exposure, subjective qualitative bias, and lack of cardiac functional assessment. This review aims to assess the methodology, diagnostic accuracy of pulmonary perfusion imaging in the current literature and discuss its advantages, limitations and future research scope.
Core Tip: Chronic thromboembolic pulmonary hypertension is an under-diagnosed disorder with high mortality if not diagnosed on time, however it can be fully cured with efficient diagnostic tools. Pulmonary perfusion magnetic resonance imaging (MRI) provides a non-invasive, reliable, radiation free and safer diagnostic test potentially replacing the standard techniques. Cardiopulmonary MRI also provides a comprehensive cardiopulmonary assessment in one single visit resulting in patients’ convenience and better utilization of healthcare resources and time.
