Pang XX, Xie L, Yao WJ, Liu XX, Pan B, Chen N. Advancements of molecular imaging and radiomics in pancreatic carcinoma. World J Radiol 2023; 15(1): 10-19 [PMID: 36721672 DOI: 10.4329/wjr.v15.i1.10]
Corresponding Author of This Article
Ni Chen, Department of Nuclear Medicine, School of Basic Medicine Anhui Medical University, No. 81 Meishan Road, Hefei 230032, Anhui Province, China. icefei@mail.ustc.edu.cn
Research Domain of This Article
Oncology
Article-Type of This Article
Minireviews
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Radiol. Jan 28, 2023; 15(1): 10-19 Published online Jan 28, 2023. doi: 10.4329/wjr.v15.i1.10
Advancements of molecular imaging and radiomics in pancreatic carcinoma
Xiao-Xi Pang, Liang Xie, Wen-Jun Yao, Xiu-Xia Liu, Bo Pan, Ni Chen
Xiao-Xi Pang, Liang Xie, Xiu-Xia Liu, Department of Nuclear Medicine, The Second Hospital of Anhui Medical University, Hefei 230601, Anhui Province, China
Wen-Jun Yao, Department of Radiology, The Second affiliated hospital of Anhui Medical University, Hefei 230601, Anhui Province, China
Bo Pan, PET/CT Center, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230001, Anhui Province, China
Ni Chen, Department of Nuclear Medicine, School of Basic Medicine Anhui Medical University, Hefei 230032, Anhui Province, China
Author contributions: Pang XX and Xie L wrote the paper; Pan B provided cases of 18F-FDG vs18F-FAPI PET/CT scan and advice on 18F-FDG vs18F-FAPI of pancreatic carcinoma; Yao WJ and Liu XX provided advice on MRI scan of pancreatic carcinoma; Chen N and Pang XX cooperated on scientific research in Gd-DOTA-HHK and 99mTc-DOTA-HHK compounds.
Supported byThe Basic and Clinical Cooperative Research Promotion Plan of Anhui Medical University, No. 2019xkjT011; Anhui Provincial Natural Science Foundation, No. 2008085QH406; and Anhui Medical University Joint Project of Nuclear Medicine and Radiation Medicine, No. 2021 Lcxk035.
Conflict-of-interest statement: The authors have declared that no conflicts of interest exist.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ni Chen, Department of Nuclear Medicine, School of Basic Medicine Anhui Medical University, No. 81 Meishan Road, Hefei 230032, Anhui Province, China. icefei@mail.ustc.edu.cn
Received: September 30, 2022 Peer-review started: September 30, 2022 First decision: October 29, 2022 Revised: November 12, 2022 Accepted: January 9, 2023 Article in press: January 9, 2023 Published online: January 28, 2023 Processing time: 109 Days and 6.5 Hours
Abstract
Despite the recent progress of medical technology in the diagnosis and treatment of tumors, pancreatic carcinoma remains one of the most malignant tumors, with extremely poor prognosis partly due to the difficulty in early and accurate imaging evaluation. This paper focuses on the research progress of magnetic resonance imaging, nuclear medicine molecular imaging and radiomics in the diagnosis of pancreatic carcinoma. We also briefly described the achievements of our team in this field, to facilitate future research and explore new technologies to optimize diagnosis of pancreatic carcinoma.
Core Tip: Pancreatic carcinoma remains high incidence and poor prognosis. Molecular imaging enables early and precise diagnosis, efficient assessment, non-invasive pathological classification. This paper aims to review the recent research progress of nuclear medicine, magnetic resonance imaging and radiomics in the diagnosis of pancreatic carcinoma, and also briefly describe our team's work in this field.