Atri L, Morgan M, Harrell S, AlJaroudi W, Berman AE. Role of cardiac magnetic resonance imaging in the diagnosis and management of COVID-19 related myocarditis: Clinical and imaging considerations. World J Radiol 2021; 13(9): 283-293 [PMID: 34630914 DOI: 10.4329/wjr.v13.i9.283]
Corresponding Author of This Article
Lavannya Atri, MS, Division of Cardiology, Medical College of Georgia, Augusta University, 1120 15th Street, Augusta, GA 30912, United States. latri@augusta.edu
Research Domain of This Article
Cardiac & Cardiovascular Systems
Article-Type of This Article
Minireviews
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Radiol. Sep 28, 2021; 13(9): 283-293 Published online Sep 28, 2021. doi: 10.4329/wjr.v13.i9.283
Role of cardiac magnetic resonance imaging in the diagnosis and management of COVID-19 related myocarditis: Clinical and imaging considerations
Lavannya Atri, Michael Morgan, Sean Harrell, Wael AlJaroudi, Adam E Berman
Lavannya Atri, Michael Morgan, Sean Harrell, Wael AlJaroudi, Adam E Berman, Division of Cardiology, Medical College of Georgia, Augusta University, Augusta, GA 30912, United States
Adam E Berman, Division of Health Policy, Medical College of Georgia, Augusta University, Augusta, GA 30912, United States
Adam E Berman, Division of Health Economics and Modeling, Medical College of Georgia, Augusta University, Augusta, GA 30912, United States
Author contributions: Atri L and Morgan M wrote the paper; Harrell S, AlJaroudi W, Berman AE made critical revisions and added content to the manuscript; Berman AE conceived the topic and provided oversight of the writing, editing and submission process.
Conflict-of-interest statement: Authors declare no conflict of interest for this article. This manuscript is not under review elsewhere and there is no prior publication of manuscript contents. The views expressed in this article are solely those of the authors.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Lavannya Atri, MS, Division of Cardiology, Medical College of Georgia, Augusta University, 1120 15th Street, Augusta, GA 30912, United States. latri@augusta.edu
Received: February 28, 2021 Peer-review started: February 28, 2021 First decision: May 6, 2021 Revised: May 27, 2021 Accepted: August 30, 2021 Article in press: August 30, 2021 Published online: September 28, 2021 Processing time: 210 Days and 1.6 Hours
Abstract
There is a growing evidence of cardiovascular complications in coronavirus disease 2019 (COVID-19) patients. As evidence accumulated of COVID-19 mediated inflammatory effects on the myocardium, substantial attention has been directed towards cardiovascular imaging modalities that facilitate this diagnosis. Cardiac magnetic resonance imaging (CMRI) is the gold standard for the detection of structural and functional myocardial alterations and its role in identifying patients with COVID-19 mediated cardiac injury is growing. Despite its utility in the diagnosis of myocardial injury in this population, CMRI’s impact on patient management is still evolving. This review provides a framework for the use of CMRI in diagnosis and management of COVID-19 patients from the perspective of a cardiologist. We review the role of CMRI in the management of both the acutely and remotely COVID-19 infected patient. We discuss patient selection for this imaging modality; T1, T2, and late gadolinium enhancement imaging techniques; and previously described CMRI findings in other cardiomyopathies with potential implications in COVID-19 recovered patients.
Core Tip: Cardiovascular magnetic resonance imaging (CMRI) is a powerful imaging modality used in defining cardiac tissue characterization. As the prevalence and incidence of coronavirus disease 2019 (COVID-19) continues to rise, the utility of CMRI in defining COVID-19 related myocardial damage is growing. This review discusses the impact of CMRI in diagnosing myocardial involvement in acutely ill and recovered COVID-19 patients as well as its implications for patient management.
