Eng-Chuan S, Kritsaneepaiboon S, Kaewborisutsakul A, Kanjanapradit K. Giant intraventricular and paraventricular cavernous malformations with multifocal subependymal cavernous malformations in pediatric patients: Two case reports. World J Radiol 2020; 12(2): 10-17 [PMID: 32180903 DOI: 10.4329/wjr.v12.i2.10]
Corresponding Author of This Article
Supika Kritsaneepaiboon, MD, Lecturer, Department of Radiology, Faculty of Medicine, Prince of Songkla University, 15 Karnjanavanich Road, Hat Yai 90110, Thailand. supikak@yahoo.com
Research Domain of This Article
Radiology, Nuclear Medicine & Medical Imaging
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Radiol. Feb 28, 2020; 12(2): 10-17 Published online Feb 28, 2020. doi: 10.4329/wjr.v12.i2.10
Giant intraventricular and paraventricular cavernous malformations with multifocal subependymal cavernous malformations in pediatric patients: Two case reports
Suwadee Eng-Chuan, Supika Kritsaneepaiboon, Department of Radiology, Faculty of Medicine, Prince of Songkla University, Hat Yai 90110, Thailand
Anukoon Kaewborisutsakul, Neurosugery Unit, Department of Surgery, Faculty of Medicine, Prince of Songkla University, Hat Yai 90110, Thailand
Kanet Kanjanapradit, Department of Pathology, Faculty of Medicine, Prince of Songkla University, Hat Yai 90110, Thailand
Author contributions: Eng-Chuan S, Kritsaneepaiboon S were the radiologists reviewed the literature, interpreted imaging findings and contributed to manuscript drafting; Kaewborisutsakul A was the patient’s neurosurgeon performed the operation, reviewed the literature and contributed to manuscript drafting; Kanjanapradit K interpreted the histologic tissue and contributed to manuscript; Eng-Chuan S, Kritsaneepaiboon S were responsible for the revision of the manuscript for important intellectual content; all authors issued final approval for the version to be submitted.
Informed consent statement: Informed consents were obtained from the patients and the information used anonymous clinical data.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Supika Kritsaneepaiboon, MD, Lecturer, Department of Radiology, Faculty of Medicine, Prince of Songkla University, 15 Karnjanavanich Road, Hat Yai 90110, Thailand. supikak@yahoo.com
Received: August 2, 2019 Peer-review started: August 2, 2019 First decision: November 6, 2019 Revised: November 21, 2019 Accepted: December 5, 2019 Article in press: December 5, 2019 Published online: February 28, 2020 Processing time: 201 Days and 10.1 Hours
Abstract
BACKGROUND
Giant cavernous malformation (GCM) is rarely found in intraventricular or paraventricular locations.
CASE SUMMARY
We present two cases of 6-mo and 21-mo boys with intraventricular and paraventricular GCMs including a literature review focused on location and imaging findings. Characteristic magnetic resonance imaging findings such as multicystic lesions and a hemosiderin ring or bubbles-of-blood appearance can assist in the differential diagnosis of a hemorrhagic intraventricular and/or paraventricular mass.
CONCLUSION
Multifocal intraventricular and/or paraventricular GCM in small children is rare. The characteristic magnetic resonance imaging findings can help to differentiate GCMs from other intraventricular tumors.
Core tip: We present two rare cases of multifocal intraventricular and/or paraventricular giant cavernous malformation (GCM) in small children including a literature review focused on location and imaging findings. The GCM is a rare entity. Intraventricular cavernous malformations are very rare and account for 2.5% of all brain cavernous malformations and are mostly found in the third ventricle. Characteristic magnetic resonance imaging findings such as multicystic lesions and a hemosiderin ring or bubbles-of-blood appearance can assist to differentiate GCMs from other intraventricular tumors/masses.
