Review
Copyright ©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Cardiol. Aug 26, 2017; 9(8): 652-666
Published online Aug 26, 2017. doi: 10.4330/wjc.v9.i8.652
Cardiovascular involvement in celiac disease
Edward J Ciaccio, Suzanne K Lewis, Angelo B Biviano, Vivek Iyer, Hasan Garan, Peter H Green
Edward J Ciaccio, Suzanne K Lewis, Peter H Green, Department of Medicine, Celiac Disease Center, Columbia University College of Physicians and Surgeons, New York, NY 10032, United States
Edward J Ciaccio, Angelo B Biviano, Vivek Iyer, Hasan Garan, Department of Medicine, Division of Cardiology, Columbia University College of Physicians and Surgeons, New York, NY 10032, United States
Author contributions: Ciaccio EJ designed the study and wrote the manuscript; Lewis SK, Biviano AB, Iyer V, Garan H and Green PH reviewed the manuscript and suggested changes.
Conflict-of-interest statement: The authors have no conflicts of interest.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Edward J Ciaccio, PhD, Department of Medicine, Celiac Disease Center, Columbia University College of Physicians and Surgeons, P and S 7-445, 630 West 168th Street, New York, NY 10032, United States. ciaccio@columbia.edu
Telephone: +1-212-3055447 Fax: +1-212-3420447
Received: February 22, 2017
Peer-review started: February 22, 2017
First decision: May 8, 2017
Revised: May 13, 2017
Accepted: June 30, 2017
Article in press: July 3, 2017
Published online: August 26, 2017
Processing time: 183 Days and 1.6 Hours
Core Tip

Core tip: Celiac disease (CD) is a public health concern suffered by about 1% of the population worldwide. It often goes undetected even in developed countries, owing to the varied and occult presentation which can make diagnosis difficult. Untreated, systemic manifestations including cardiovascular ailments can occur. In this review, information concerning the cardiovascular involvement in CD patients is described and discussed. Treatment of CD patients with a gluten free diet can reverse some, but not all of the cardiovascular involvement. Thus the need for prompt diagnosis and treatment.