Meta-Analysis
Copyright ©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Cardiol. Dec 26, 2017; 9(12): 830-837
Published online Dec 26, 2017. doi: 10.4330/wjc.v9.i12.830
Erythropoietin therapy after out-of-hospital cardiac arrest: A systematic review and meta-analysis
Rahul Chaudhary, Jalaj Garg, Parasuram Krishnamoorthy, Kevin Bliden, Neeraj Shah, Nayan Agarwal, Rahul Gupta, Abhishek Sharma, Karl B Kern, Nainesh C Patel, Paul Gurbel
Rahul Chaudhary, Department of Medicine, Sinai Hospital of Baltimore, Baltimore, MD 21215, United States
Jalaj Garg, Neeraj Shah, Nainesh C Patel, Division of Cardiology, Lehigh Valley Health Network, Allentown, PA 18103, United States
Parasuram Krishnamoorthy, Department of Medicine, Division of Cardiology, Einstein Healthcare Network, Philadelphia, PA 19141, United States
Kevin Bliden, Paul Gurbel, Inova Heart and Vascular Institute, Inova Medical Center, Fairfax, VA 22042, United States
Nayan Agarwal, Division of Cardiovascular Medicine, University of Florida, Gainesville, FL 32611, United States
Rahul Gupta, Queens Cardiac Care, Queens, NY 11428, United States
Abhishek Sharma, Division of Cardiovascular Medicine, State University of New York, Brooklyn, NY 12246, United States
Karl B Kern, Division of Cardiology, University of Arizona College of Medicine, Tucson, AZ 85721, United States
Author contributions: All the authors contributed to this manusscript; Chaudhary R and Garg J contributed equally to this work.
Conflict-of-interest statement: All authors report no conflicts of interest.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Jalaj Garg, MD, FESC, Division of Cardiology, Lehigh Valley Health Network, 1250 S Cedar Crest Blvd, Allentown, PA 18103, United States. jalaj.garg@lvhn.org
Telephone: +1-585-7660898 Fax: +1-610-4023225
Received: June 15, 2017
Peer-review started: June 19, 2017
First decision: July 17, 2017
Revised: November 6, 2017
Accepted: November 22, 2017
Article in press: November 22, 2017
Published online: December 26, 2017
Processing time: 189 Days and 8 Hours
Core Tip

Core tip: This manuscript suggested that: (1) No improvement in neurological outcomes with erythropoietin (Epo) administration after out of hospital cardiac arrest; and (2) Epo administration was also associated with increased thrombotic events and acute stent thrombosis.