Copyright
©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Cardiac remodeling and physical training post myocardial infarction
Michael A Garza, Emily A Wason, John Q Zhang, Laboratory of Cardiovascular Research, Department of Health, Kinesiology, and Nutrition, University of Texas at San Antonio, San Antonio, TX 78249, United States
Author contributions: Zhang JQ designed and contributed to writing and edited the manuscript; Garza MA participated in designing and writing the manuscript; Wason EA contributed to writing and formulating the manuscript.
Conflict-of-interest: The authors have no any conflict-of-interest related to this manuscript.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: John Q Zhang, PhD, Professor, Director of Laboratory of Cardiovascular Research, Department of Health, Kinesiology, and Nutrition, University of Texas at San Antonio, 1 UTSA Circle, San Antonio, TX 78249, United States. john.zhang@utsa.edu
Telephone: +1-210-4587390 Fax: +1-210-4585873
Received: May 29, 2014
Peer-review started: May 29, 2014
First decision: July 18, 2014
Revised: December 31, 2014
Accepted: January 15, 2015
Article in press: January 19, 2015
Published online: February 26, 2015
Processing time: 258 Days and 10.7 Hours
Peer-review started: May 29, 2014
First decision: July 18, 2014
Revised: December 31, 2014
Accepted: January 15, 2015
Article in press: January 19, 2015
Published online: February 26, 2015
Processing time: 258 Days and 10.7 Hours
Core Tip
Core tip: After myocardial infarction, the heart undergoes extensive myocardial remodeling through the accumulation of fibrous tissue in both the infarcted and noninfarcted myocardium, which distorts tissue structure, increases tissue stiffness, and accounts for ventricular dysfunction. There is growing clinical consensus that exercise training may beneficially alter the course of post-myocardial infarction (MI) myocardial remodeling and improve cardiac function. This review summarizes the present state of knowledge regarding the effect of post-MI exercise training on infarcted hearts.