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World J Cardiol. Dec 26, 2015; 7(12): 882-888
Published online Dec 26, 2015. doi: 10.4330/wjc.v7.i12.882
Space radiation and cardiovascular disease risk
Marjan Boerma, Gregory A Nelson, Vijayalakshmi Sridharan, Xiao-Wen Mao, Igor Koturbash, Martin Hauer-Jensen
Marjan Boerma, Vijayalakshmi Sridharan, Martin Hauer-Jensen, Division of Radiation Health, Department of Pharmaceutical Sciences, University of Arkansas for Medical Sciences, Little Rock, AR 72205, United States
Gregory A Nelson, Xiao-Wen Mao, Department of Basic Sciences, Loma Linda University, Loma Linda, CA 92354, United States
Gregory A Nelson, Xiao-Wen Mao, Department of Radiation Medicine, Loma Linda University, Loma Linda, CA 92354, United States
Igor Koturbash, Department of Environmental and Occupational Health, University of Arkansas for Medical Sciences, Little Rock, AR 72205, United States
Martin Hauer-Jensen, Central Arkansas Veterans Healthcare System, Surgical Service, Little Rock, AR 72205, United States
Author contributions: Mao XW and Koturbash I provided research data; Boerma M and Sridharan V wrote the paper; Nelson GA and Hauer-Jensen M provided expert input and edited the paper.
Supported by The National Space Biomedical Research Institute (RE03701) through NCC 9-58; and the National Institutes of Health (CA148679 and P20 GM109005).
Conflict-of-interest statement: The authors have no conflicts of interest to declare.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Marjan Boerma, PhD, Division of Radiation Health, Department of Pharmaceutical Sciences, University of Arkansas for Medical Sciences, 4301 West Markham, Slot 522-10, Little Rock, AR 72205, United States. mboerma@uams.edu
Telephone: +1-501-6866599 Fax: +1-501-6866057
Received: May 29, 2015
Peer-review started: June 3, 2015
First decision: August 4, 2015
Revised: August 18, 2015
Accepted: October 1, 2015
Article in press: October 8, 2015
Published online: December 26, 2015
Core Tip

Core tip: This review article provides an overview of studies in experimental models that have begun to shed light on the potential risks of damage in heart and blood vessels after exposure to space radiation.