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World J Cardiol. Oct 26, 2015; 7(10): 658-664
Published online Oct 26, 2015. doi: 10.4330/wjc.v7.i10.658
Is there a rationale for short cardioplegia re-dosing intervals?
Yves D Durandy
Yves D Durandy, Department of Intensive Care and Perfusion, Centre Chirurgical Marie Lannelongue, F-92350 Le Plessis, Robinson, France
Author contributions: Durandy YD solely contributed to this paper.
Conflict-of-interest statement: I do declare that I have no conflicting interest including but not limited to commercial, personal, political, intellectual, or religious interests.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Yves D Durandy, MD, Consultant, Department of Intensive Care and Perfusion, Centre Chirurgical Marie Lannelongue, Avenue de la Résistance, F-92350 Le Plessis, Robinson, France. yves.durandy@gmail.com
Telephone: +33-661-697416
Received: May 26, 2015
Peer-review started: May 29, 2015
First decision: August 4, 2015
Revised: August 16, 2015
Accepted: September 10, 2015
Article in press: September 16, 2015
Published online: October 26, 2015
Processing time: 160 Days and 14.1 Hours
Core Tip

Core tip: During myocardial ischemia, cardioplegia is the preferred method of myocardial protection. However, decades after its implementation, there is still no consensus on the optimal re-dosing interval. Shorter re-dosing (15-30 min) has been preferred to longer intervals (45-60 min), but the choice of one approach over another relies more on the surgeon’s preference than on clear advantages. As the interest for one-shot cardioplegia has been increasing recently, we intend to discuss the rationale, if any, for short cardioplegia re-dosing interval.