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World J Cardiol. May 26, 2014; 6(5): 338-344
Published online May 26, 2014. doi: 10.4330/wjc.v6.i5.338
Published online May 26, 2014. doi: 10.4330/wjc.v6.i5.338
Heart and lung, a dangerous liaison-Tako-tsubo cardiomyopathy and respiratory diseases: A systematic review
Roberto Manfredini, Fabio Fabbian, Alfredo De Giorgi, Marco Pala, Alessandra Mallozzi Menegatti, Claudia Parisi, Elisa Misurati, Ruana Tiseo, Clinica Medica, Azienda Ospedaliera-Universitaria of Ferrara, 44124 Cona, Ferrara, Italy
Massimo Gallerani, 1st Internal Medicine Unit, Azienda Ospedaliera-Universitaria of Ferrara, 44124 Cona, Ferrara, Italy
Raffaella Salmi, 2nd Internal Medicine Unit, Azienda Ospedaliera-Universitaria of Ferrara, 44124 Cona, Ferrara, Italy
Eduardo Bossone, Cardiology Unit, Azienda Ospedaliera-Universitaria of Salerno, 84131 Salerno, Italy
Author contributions: Manfredini R and Bossone E equally contributed to the work; Manfredini R, Fabbian F, Gallerani M, Salmi R, Bossone E designed the research; De Giorgi A, Pala M, Mallozzi Menegatti A, Parisi C, Misurati E, Tiseo R searched the available literature, found the articles, and performed the research; Manfredini R, Fabbian F, De Giorgi A, Pala M, Mallozzi Menegatti A, Parisi C, Misurati E, Tiseo R analyzed the data; Manfredini R, Fabbian F, Bossone E, Gallerani M wrote the paper; Manfredini R, Fabbian F, De Giorgi A, Pala M, Mallozzi Menegatti A, Parisi C, Misurati E, Tiseo R, Gallerani M, Salmi R, Bossone E revised critically the manuscript for intellectual and conceptual content, and approved the final version; Manfredini R collected funds.
Supported by A scientific grant (FAR–Fondo Ateneo Ricerca) from the University of Ferrara, Italy (in part)
Correspondence to: Roberto Manfredini, MD, Clinica Medica, Azienda Ospedaliera-Universitaria of Ferrara, Via Aldo Moro 8, 44124 Cona, Ferrara, Italy. roberto.manfredini@unife.it
Telephone: +39-0532-237166 Fax: +39-0532-236816
Received: December 21, 2013
Revised: March 11, 2014
Accepted: April 17, 2014
Published online: May 26, 2014
Processing time: 183 Days and 24 Hours
Revised: March 11, 2014
Accepted: April 17, 2014
Published online: May 26, 2014
Processing time: 183 Days and 24 Hours
Core Tip
Core tip: This is the first study evaluating the association between respiratory diseases and Tako-Tsubo cardiomyopathy (TTC). Patients with severe respiratory diseases, due to the high dosages of β2-agonists used or to the need of invasive procedures, are highly exposed to the risk of developing TTC. Thus, in these patients a certain caution should maintained, along with a special alertness in suspecting and recognizing this particular disease.