Topic Highlight
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World J Cardiol. May 26, 2014; 6(5): 227-233
Published online May 26, 2014. doi: 10.4330/wjc.v6.i5.227
Management of hypertension in primary aldosteronism
Anna Aronova, Thomas J Fahey III, Rasa Zarnegar
Anna Aronova, Thomas J Fahey III, Rasa Zarnegar, Department of Surgery, Weill Cornell Medical College/New York Presbyterian Hospital, New York, NY 10021, United States
Author contributions: Aronova A, Fahey III TJ and Zarnegar R contributed equally to the conception and acquisition of data, drafting and revision the manuscript for intellectual content and approving the final version for publication.
Correspondence to: Rasa Zarnegar, MD, Department of Surgery, Weill Cornell Medical College/New York Presbyterian Hospital, 585 East 68th Street, A1027, New York, NY 10021, United States. raz2002@med.cornell.edu
Telephone: +1-212-7465130 Fax: +1-212-7469948
Received: December 29, 2013
Revised: February 20, 2014
Accepted: April 16, 2014
Published online: May 26, 2014
Core Tip

Core tip: Primary hyperaldosteronism is the most common reversible form of secondary hypertension. After appropriate diagnosis and localization studies, adrenalectomy is the procedure of choice for unilateral aldosterone-secreting adenomas, while medical therapy is best for bilateral adrenal hyperplasia. Surgical resection improves or cures biochemical and hemodynamic perturbations in most patients, and halts or reverses many of the deleterious effects of hyperaldosteronism. Predicting which patients will benefit most from adrenalectomy is aided by the Aldosteronoma Resolution Score.