Retrospective Cohort Study
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Cardiol. Feb 26, 2025; 17(2): 99074
Published online Feb 26, 2025. doi: 10.4330/wjc.v17.i2.99074
Outcomes of patients with acute ST-segment elevation myocardial infarction treated by a prolonged “Deferred” percutaneous coronary intervention strategy
Akshyaya Pradhan, Shivam Uppal, Pravesh Vishwakarma, Abhishek Singh, Monika Bhandari, Ayush Shukla, Akhil Sharma, Gaurav Chaudhary, Sharad Chandra, Rishi Sethi, Sudhanshu Kumar Dwivedi
Akshyaya Pradhan, Abhishek Singh, Monika Bhandari, Ayush Shukla, Akhil Sharma, Gaurav Chaudhary, Sharad Chandra, Rishi Sethi, Department of Cardiology, King George’s Medical University, Lucknow 226003, Uttar Pradesh, India
Shivam Uppal, Department of Cardiology, Pushpanjali Hospital, Rewari 123401, Haryāna, India
Pravesh Vishwakarma, Sudhanshu Kumar Dwivedi, Cardiology Centre, King George’s Medical University, Lucknow 226003, Uttar Pradesh, India
Author contributions: Pradhan A, Uppal S, Vishwakarma P, Singh A, Bhandari M, Shukla A, Sharma A, Chaudhary G, Chandra S, Sethi R, and Dwivedi SK contributed equally to the conceptualization and design, material preparation, writing-draft manuscript, writing-revision, and approved submission of the final version.
Institutional review board statement: The study is approved by the institutional review board (Approval letter no. 503/Ethics/19).
Informed consent statement: Written informed consent was obtained from all participants or their legal guardians.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
STROBE statement: The authors have read the STROBE Statement-checklist of items, and the manuscript was prepared and revised according to the STROBE Statement-checklist of items.
Data sharing statement: Dataset will be made available on request by the corresponding author at drmonikab@gmail.com.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Monika Bhandari, DM, MD, Doctor, Department of Cardiology, King George’s Medical University, Shahmina Road, Chowk, Lucknow 226003, Uttar Pradesh, India. drmonikab@gmail.com
Received: July 12, 2024
Revised: October 8, 2024
Accepted: January 17, 2025
Published online: February 26, 2025
Processing time: 227 Days and 16 Hours
Core Tip

Core Tip: This study evaluated the effectiveness and safety of a deferred percutaneous coronary intervention (PCI) strategy in patients with ST-segment elevation myocardial infarction (STEMI). The deferred PCI approach led to significant reductions in thrombus burden, improved thrombolysis in myocardial infarction (TIMI) flow, and enhanced myocardial blush grade. It also minimized the incidence of slow-flow/no-flow events and prevented unnecessary stent deployments. These findings suggest that deferred PCI is a promising strategy to manage STEMI patients with high thrombus burden, offering better angiographic and clinical outcomes by optimizing intervention timing and reducing complications.