Editorial
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Cardiol. May 26, 2024; 16(5): 226-230
Published online May 26, 2024. doi: 10.4330/wjc.v16.i5.226
Cardiovascular mechanisms of thyroid hormones and heart failure: Current knowledge and perspectives
Viktor Čulić
Viktor Čulić, Department of Cardiology and Angiology, University Hospital Centre Split, University of Split School of Medicine, Split 21000, Croatia
Author contributions: Čulić V wrote this editorial, consulted and analysed literature, and created tables.
Conflict-of-interest statement: Prof. Čulić has nothing to disclose.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Viktor Čulić, MD, PhD, Full Professor, Senior Scientist, Department of Cardiology and Angiology, University Hospital Centre Split, University of Split School of Medicine, Šoltanska 2, Split 21000, Croatia. viktor.culic@st.t-com.hr
Received: December 24, 2023
Revised: April 12, 2024
Accepted: April 18, 2024
Published online: May 26, 2024
Processing time: 150 Days and 17.7 Hours
Core Tip

Core Tip: The non-thyroidal illness syndrome, also referred to as euthyroid sick syndrome or low triiodothyronine syndrome, can be found in about 30% of patients with heart failure (HF). Serum total triiodothyronine levels and the ratio of free triiodothyronine to free thyroxine seem to correlate the best with the echocardiographic, laboratory and clinical parameters of the severity of HF. Future research should further explore cellular and tissue mechanisms of this syndrome as well as possible therapeutic options in patients with HF.