Retrospective Study
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Cardiol. Apr 26, 2023; 15(4): 154-164
Published online Apr 26, 2023. doi: 10.4330/wjc.v15.i4.154
Vasospastic angina in women: Clinical backgrounds and prognoses of patients younger than and older than 60 years
Hiroki Teragawa, Chikage Oshita, Yuko Uchimura
Hiroki Teragawa, Chikage Oshita, Yuko Uchimura, Department of Cardiovascular Medicine, JR Hiroshima Hospital, Hiroshima 732-0057, Japan
Author contributions: Oshita C and Uchimura Y contributed to the acquisition of data and Teragawa H contributed to the writing and revision of the manuscript; All the authors approved the final version of the manuscript.
Institutional review board statement: The study was reviewed and approved by the JR Hiroshima Hospital Institutional Review Board (Approval No. 2022-38).
Informed consent statement: Patients were not required to give informed consent to the study because the analysis used anonymous clinical data that were obtained after each patient agreed to treatment by written consent. Furthermore, in the retrospective cohort study, we have shown the information about the present study, on our web site (http://www.jrhh.sakura.ne.jp/annnai/torikumi.html), as an opt-out method.
Conflict-of-interest statement: All the authors declare that they have no conflict of interest.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Hiroki Teragawa, FACC, FACP, FAHA, FESC, MD, PhD, Chief Physician, Doctor, Department of Cardiovascular Medicine, JR Hiroshima Hospital, 3-1-36 Futabanosato, Higashi-ku, Hiroshima 732-0057, Japan. hiroki-teragawa@jrhh.or.jp
Received: January 11, 2023
Peer-review started: January 11, 2023
First decision: January 31, 2023
Revised: February 6, 2023
Accepted: April 7, 2023
Article in press: April 7, 2023
Published online: April 26, 2023
Processing time: 99 Days and 4.8 Hours
Core Tip

Core Tip: We investigated whether the clinical background and prognosis of women aged < 60 years with vasospastic angina (VSA) differ from those of women aged ≥ 60 years with VSA. We showed that smoking was more frequent in women aged < 60 years with VSA. We found a significantly greater peripheral vascular response to nitroglycerin in such patients. Coronary angiography revealed fewer atherosclerotic lesions and focal spasms in such patients. Smoking status and vascular dysfunction may have influenced the above clinical characteristics in women aged < 60 years with VSA.