Case Report
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Cardiol. Nov 26, 2023; 15(11): 609-614
Published online Nov 26, 2023. doi: 10.4330/wjc.v15.i11.609
Hypertrophic cardiomyopathy secondary to deficiency in lysosome-associated membrane protein-2: A case report
Ye-Tong Zhao, Xiu-Qun Cao, Xiao-Lin Mu
Ye-Tong Zhao, Xiao-Lin Mu, Department of Radiology, Central Hospital of Dalian University of Technology, Dalian 116033, Liaoning Province, China
Ye-Tong Zhao, Graduate School, Dalian Medical University, Dalian 116000, Liaoning Province, China
Xiu-Qun Cao, Departments of Ultrasound and Health Medicine, Central Hospital of Dalian University of Technology, Dalian 116033, Liaoning Province, China
Author contributions: Cao XQ and Mu XL collected the clinical data; Mu XL and Zhao YT analyzed and interpreted the clinical data; Zhao YT drafted the manuscript; Mu XL guided the completion of this article, supervising and revising the manuscript for intellectual content; All of the authors have read and approved the final manuscript.
Informed consent statement: Written informed consent was obtained from the patient’s parents for the publication of this report and any accompanying images.
Conflict-of-interest statement: All the authors have no conflicts of interest to declare.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Xiao-Lin Mu, MS, Doctor, Department of Radiology, Central Hospital of Dalian University of Technology, No. 826 Southwest Road, Shahekou District, Dalian 116033, Liaoning Province, China. dugumuxin@163.com
Received: August 23, 2023
Peer-review started: August 23, 2023
First decision: October 9, 2023
Revised: October 19, 2023
Accepted: November 3, 2023
Article in press: November 3, 2023
Published online: November 26, 2023
Processing time: 91 Days and 18.2 Hours
Core Tip

Core Tip: Danon disease (DD) is a rare X-linked disorder caused by a deficiency of lysosome-associated membrane protein-2. DD is clinically characterized by severe cardiomyopathy, skeletal muscle disease, and intellectual disability. The most frequent high-risk form of DD is cardiomyopathy, which can result in arrhythmia(s), early-onset heart failure, and even sudden cardiac death. Our case report intents to raise the awareness of DD and improve the clinical suspicion of DD.