Observational Study
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World J Cardiol. Aug 26, 2022; 14(8): 462-472
Published online Aug 26, 2022. doi: 10.4330/wjc.v14.i8.462
Cardiometabolic risk factors in young Indian men and their association with parameters of insulin resistance and beta-cell function
Yashdeep Gupta, Alpesh Goyal, Mani Kalaivani, Nikhil Tandon
Yashdeep Gupta, Alpesh Goyal, Nikhil Tandon, Department of Endocrinology and Metabolism, All India Institute of Medical Sciences, New Delhi 110029, Delhi, India
Mani Kalaivani, Department of Biostatistics, All India Institute of Medical Sciences, New Delhi 110029, Delhi, India
Author contributions: Gupta Y conceived the idea and wrote the manuscript; Goyal A, Kalaivani M, and Tandon N read and edited the manuscript; Kalaivani M did the statistical analysis; all authors approved the final version of this manuscript.
Institutional review board statement: This is a post-hoc analysis of the data collected in two previously published studies that primarily evaluated the concordance of cardiometabolic risk factors among spouses of women with hyperglycaemia in pregnancy. Both studies were approved by the institutional ethics committee, and written informed consent was obtained from all participants.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: Yashdeep Gupta, Alpesh Goyal, Mani Kalaivani, and Nikhil Tandon have nothing to disclose for this article.
Data sharing statement: Data can be shared on reasonable request to the corresponding author
STROBE statement: The authors have read the STROBE Statement—checklist of items, and the manuscript was prepared and revised according to the STROBE Statement—checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yashdeep Gupta, MD, Additional Professor, Department of Endocrinology and Metabolism, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, Delhi, India. yash_deep_gupta@yahoo.co.in
Received: March 1, 2022
Peer-review started: March 1, 2022
First decision: April 17, 2022
Revised: April 29, 2022
Accepted: July 20, 2022
Article in press: July 20, 2022
Published online: August 26, 2022
Processing time: 170 Days and 9.7 Hours
Core Tip

Core Tip: There is an unmet need to evaluate the burden of cardiometabolic risk factors in young South Asian adults, who are not preselected for glycaemia. Against this backdrop, this study aimed to evaluate young North Indian men (aged 20-50 years) for: (1) Burden of glycemic and cardiometabolic traits; and (2) Their relation to parameters of insulin action and beta-cell function.