Bhandari M, Pradhan A, Vishwakarma P, Sethi R. Coronavirus and cardiovascular manifestations- getting to the heart of the matter. World J Cardiol 2021; 13(10): 556-565 [PMID: 34754400 DOI: 10.4330/wjc.v13.i10.556]
Corresponding Author of This Article
Akshyaya Pradhan, MBBS, MD, DM, FACC, FSCAI Additional Professor, Department of Cardiology, King George's Medical University, Shahmina Road, Chowk, Lucknow 226003, Uttar Pradesh, India. akshyaya33@gmail.com
Research Domain of This Article
Cardiac & Cardiovascular Systems
Article-Type of This Article
Minireviews
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Monika Bhandari, Akshyaya Pradhan, Pravesh Vishwakarma, Rishi Sethi, Department of Cardiology, King George's Medical University, Lucknow 226003, Uttar Pradesh, India
Author contributions: Pradhan A and Bhandari M conceived the project; Pradhan A and Vishwakarma P did the literature review; Bhandari M prepared the first draft; Sethi R critically reviewed it; Bhandari M and Vishwakarma P prepared the revised manuscript; Pradhan A submitted the original manuscript and collaborated with Bhandari M for revising the manuscript and submitted it.
Conflict-of-interest statement: The authors declare that there are no conflicts of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Akshyaya Pradhan, MBBS, MD, DM, FACC, FSCAI Additional Professor, Department of Cardiology, King George's Medical University, Shahmina Road, Chowk, Lucknow 226003, Uttar Pradesh, India. akshyaya33@gmail.com
Received: June 21, 2021 Peer-review started: June 21, 2021 First decision: July 30, 2021 Revised: August 7, 2021 Accepted: September 16, 2021 Article in press: September 16, 2021 Published online: October 26, 2021 Processing time: 121 Days and 22.7 Hours
Core Tip
Core Tip: Coronavirus affects various parts of cardiovascular (CV) system. Acute coronary syndromes, myocarditis, tachyarrhythmia, heart failure and shock can be the various manifestations. The mechanism of cardiac involvement can be direct or indirect via cytokine storm ,inflammation and thromboembolism. Thromboembolism is particularly more common in coronavirus disease (COVID) infection and so is bleeding making anticoagulation a daunting task. Management of cardiac manifestations is not very different from a non COVID patient and needs diligent effort due to the need for preventing transmission to health care workers. Undoubtedly, cardiac involvement portends poor prognosis and antecedent cardiovascular disease is abundant among non-survivors. Adequate control of CV risk factors, prompt recognition of symptoms, timely management and early vaccination hold the key to victory against the coronavirus onslaught on the heart. Reports of thromboembolism have also emerged after COVID-19 vaccination but the incidence is rare.
