Meta-Analysis
Copyright ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Cardiol. Nov 26, 2020; 12(11): 571-583
Published online Nov 26, 2020. doi: 10.4330/wjc.v12.i11.571
Transradial vs transfemoral secondary access outcomes in transcatheter aortic valve implantation: A systematic review and meta-analysis
Shree Lata Radhakrishnan, Kalon KL Ho
Shree Lata Radhakrishnan, Division of General Medicine, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02215, United States
Kalon KL Ho, Division of Cardiovascular Medicine, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02215, United States
Author contributions: Radhakrishnan SL completed conceptualization, methodology and formal analysis, wrote original draft, reviewed and edited the manuscript; Ho KKL provided resources and supervision, reviewed and edited the manuscript.
Conflict-of-interest statement: All of the authors report that they have no conflicts of interest to disclose related to this research.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 checklist and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Shree Lata Radhakrishnan, MD, Division of General Medicine, Department of Medicine, Beth Israel Deaconess Medical Center, 330 Brookline Avenue W Span 210, Boston, MA 02215, United States. sradhak1@bidmc.harvard.edu
Received: August 21, 2020
Peer-review started: August 21, 2020
First decision: October 5, 2020
Revised: October 21, 2020
Accepted: October 30, 2020
Article in press: October 30, 2020
Published online: November 26, 2020
Processing time: 97 Days and 4.7 Hours
Core Tip

Core Tip: Transcatheter aortic valve implantation (TAVI) procedures can result in complications due to secondary access site. This meta-analysis looks into 5 observational studies that compared outcomes in TAVI related to secondary access. The outcomes included 30-d bleeding, vascular complications, strokes, and mortality. Meta-analysis showed decreased odds of outcomes when transradial secondary access was used over transfemoral.