Review
Copyright ©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Cardiol. Nov 26, 2019; 11(11): 266-276
Published online Nov 26, 2019. doi: 10.4330/wjc.v11.i11.266
Multi-modality imaging in transthyretin amyloid cardiomyopathy
Bryan Paul Traynor, Aamir Shamsi, Victor Voon
Bryan Paul Traynor, Department of Cardiology, Connolly Hospital Blanchardstown, Abbottstown, Dublin D15X40D, Ireland
Aamir Shamsi, Victor Voon, Department of Cardiology, St George’s University Hospital NHS Foundation Trust, London SW170QT, United Kingdom
Author contributions: Voon V and Traynor BP conceived of the initial idea of the study. Traynor BP acquired the data for publication and drafted the article. All authors revised it critically for important intellectual content. All authors approved the final version of the manuscript to be submitted.
Conflict-of-interest statement: The author declare they have no potential conflict of interest.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Victor Voon, MD, MBChB, MRCP, Doctor, Clinical Fellow in Cardiovascular Imaging, Department of Cardiology, St George’s University Hospital NHS Foundation Trust, Cranmer Terrace, Tooting, London SW170QT, United Kingdom. victor.voon@nhs.net
Telephone: +44-20-87251220 Fax: +44-20-87253178
Received: April 22, 2019
Peer-review started: April 23, 2019
First decision: August 2, 2019
Revised: September 8, 2019
Accepted: October 6, 2019
Article in press: October 6, 2019
Published online: November 26, 2019
Processing time: 215 Days and 12.4 Hours
Core Tip

Core tip: Non-invasive diagnosis of transthyretin amyloid (TTR) cardiomyopathy is improving with significant developments in multiple imaging modalities available to date. A greater appreciation of the various strengths and limitations of these imaging modalities is vital, as is high clinical suspicion and timely investigation for the disease, which remains insidious and elusive. This is of particular relevance in light of emerging novel effective therapeutic options. This focused review aims to highlight the role of multimodality imaging in the diagnosis and risk stratification of patients with TTR cardiomyopathy.