Systematic Reviews
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Cardiol. Aug 26, 2023; 15(8): 395-405
Published online Aug 26, 2023. doi: 10.4330/wjc.v15.i8.395
Use of intravascular lithotripsy in non-coronary artery lesions
Chukwuemeka Anthony Umeh, Ashley Stratton, Tifani Wagner, Shipra Saigal, Krystal Sood, Raghav Dhawan, Cory Wagner, Jessica Obi, Sabina Kumar, Tsung Han Scottie Ching, Rahul Gupta
Chukwuemeka Anthony Umeh, Ashley Stratton, Tifani Wagner, Shipra Saigal, Krystal Sood, Raghav Dhawan, Cory Wagner, Jessica Obi, Tsung Han Scottie Ching, Internal Medicine, Hemet Global Medical Center, Hemet, CA 92543, United States
Sabina Kumar, Department of Cardiology, Mclaren Macomb-Oakland/Michigan State University, Macomb, MI 48043, United States
Rahul Gupta, Internal Medicine, University of California, San Diego, CA 92122, United States
Author contributions: All authors conceptualized and revised the study design; Stratton A, Wagner T, Saigal S, Sood K, Dhawan R, and Wagner C extracted the data; Umeh CA analyzed the data; Umeh CA and Gupta R wrote the first draft of the paper; Ching THS, Kumar S, Obi J, Gupta R, and Umeh CA reviewed and revised the paper; Stratton A led and coordinated the research and writing of the manuscript; Scottie C, Gupta R, and Umeh CA supervised the project; and all authors have read and approved the final manuscript.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Chukwuemeka Anthony Umeh, MD, Attending Doctor, Internal Medicine, Hemet Global Medical Center, 1117 E Devonshire Avenue, Hemet, CA 92543, United States. emmyumeh@gmail.com
Received: March 12, 2023
Peer-review started: March 12, 2023
First decision: June 15, 2023
Revised: June 25, 2023
Accepted: July 24, 2023
Article in press: July 24, 2023
Published online: August 26, 2023
Processing time: 162 Days and 3.1 Hours
ARTICLE HIGHLIGHTS
Research background

Peripheral arterial disease (PAD) is a common manifestation of atherosclerotic disease globally, and heavy calcifications in peripheral artery diseases reduce the success of endovascular therapy for PAD. Intravascular lithotripsy (IVL) has emerged as a technique for plaque modification of severely calcified artery lesions.

Research motivation

Most of the focus of IVL has been on treating coronary artery diseases, and its use in peripheral arteries has not been extensively studied.

Research objectives

To analyze the use of IVL in the peripheral arteries, its safety, and efficacy, as reported in case reports.

Research methods

We searched and extracted cases from PubMed, EMBASE, and Reference Citation Analysis databases. Then, we did a quantitative and qualitative analysis of case reports on IVL use in peripheral artery diseases.

Research results

IVL was successfully and safely used in heavily calcified lesions in the iliofemoral artery, aortic arch and necks arteries, mesenteric arteries, renal arteries, and aorta, with the iliofemoral artery being the commonest site reported. Adverse effects were minimal, but the most severe was reported in IVL use in the neck arteries.

Research conclusions

IVL has been safely used in a broadening array of complex, severely calcified peripheral artery disease lesions.

Research perspectives

More extensive studies are needed to assess the safety of IVL in peripheral artery vessels, such as the aortic arch and necks arteries, where it is not currently approved for use.