Case Report
Copyright ©2012 Baishideng Publishing Group Co., Limited. All rights reserved.
World J Cardiol. Jun 26, 2012; 4(6): 211-213
Published online Jun 26, 2012. doi: 10.4330/wjc.v4.i6.211
Repeat recurrence of takotsubo cardiomyopathy related to inhaled beta-2-adrenoceptor agonists
Ivan Mendoza, Gian M Novaro
Ivan Mendoza, Gian M Novaro, Department of Cardiology, Cleveland Clinic Florida, Weston, FL 33331, United States
Author contributions: Mendoza I and Novaro GM contributed equally to this work.
Correspondence to: Ivan Mendoza, MD, Department of Cardiology, Cleveland Clinic Florida, Desk A23, Weston, Fl 33331, United States. ivanovich13@hotmail.com
Telephone: +1-954-6595000 Fax: +1-954-6595292
Received: December 1, 2011
Revised: May 29, 2012
Accepted: June 5, 2012
Published online: June 26, 2012
Abstract

Takotsubo cardiomyopathy (also referred to as transient apical ballooning syndrome, broken heart syndrome or stress cardiomyopathy) is an increasingly recognized entity in the western world typically characterized by reversible left ventricular dysfunction that develops in the setting of acute severe emotional or physical stress. Increased catecholamine levels have been proposed to play a central role in the pathogenesis of the disease, although the specific pathophysiology of this condition remains elusive at the present moment. In recent times, there have been reports of takotsubo cardiomyopathy (TC) following medical interventions such as invasive or surgical procedures or specific medical regimens. In the current report, we present a patient with multiple recurrences of TC triggered by the same medical therapeutic intervention; in our particular case, repetitive exposure to inhaled beta-2-adrenoceptor agonist.

Keywords: Takotsubo; Beta-2-adrenoreceptor agonist; Recurrence; Ventricular dysfunction; Heart failure