Published online Dec 26, 2012. doi: 10.4330/wjc.v4.i12.341
Revised: October 20, 2012
Accepted: October 27, 2012
Published online: December 26, 2012
AIM: To examine the feasibility and reliability of measuring global and segmental longitudinal strain (LS) compared to visual assessment of wall motion (WM).
METHODS: Assessment of segmental (17 left ventricular segments) LS using automatic function imaging (AFI) in 55 patients (60.0 ± 8.7 years, 73% male) divided into 2 groups: group I included 35 patients with WM abnormalities and/or impaired ejection fraction and group II included 20 patients with normal WM and ejection fraction. Visual analysis of WM abnormalities was performed using 2-dimensional echocardiography (2DE) and WM score was calculated. Both modalities were analyzed by one expert reader at 2 different sessions.
RESULTS: Analysis of 935 left ventricular segments was completed in 94.1% and 96.3% by visual assessment and AFI, respectively. There was a strong positive linear relationship between the WM score and global LS in all patients. Intra-observer agreement for calculation of WM score was excellent for group I patients (kappa: 0.97) and very good for group II patients (kappa: 0.92). Intra-observer agreement for AFI showed excellent agreement with very small mean difference in both group I and II (-0.0 ± 2.3 and -0.0 ± 1.9, respectively).
CONCLUSION: The interpretation of global and segmental LS using AFI is a more feasible and reliable technique for the quantification of myocardial deformation than visual assessment of WM scores.