Autobiography of Editorial Board Members
Copyright ©2011 Baishideng Publishing Group Co., Limited. All rights reserved.
World J Cardiol. Apr 26, 2011; 3(4): 121-126
Published online Apr 26, 2011. doi: 10.4330/wjc.v3.i4.121
Molecular biology of heart disease
Robert Roberts
Robert Roberts, Ruddy Canadian Cardiovascular Genetics Centre, University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, Ontario, K1Y 4W7, Canada
Author contributions: Roberts R solely contributed to this manuscript.
Supported by NHLBI, American Heart Association, Canadian Institutes of Health Research, Canadian Foundation for Innovation, Heart and Stroke Ontario
Correspondence to: Robert Roberts, MD, FRCPC, MACC, President and CEO, Professor of Medicine and Director, Ruddy Canadian Cardiovascular Genetics Centre, University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, Ontario, K1Y 4W7, Canada. rroberts@ottawaheart.ca
Telephone: +1-613-7614779 Fax: +1-613-7614650
Received: September 13, 2010
Revised: April 13, 2011
Accepted: April 20, 2011
Published online: April 26, 2011
Abstract

Dr. Robert Roberts is currently Professor of Medicine and Director of the Ruddy Canadian Cardiovascular Genetics Centre along with being President and CEO of the University of Ottawa Heart Institute. Prior to this appointment, he was Chief of Cardiology for 23 years at Baylor College of Medicine, Houston, Texas. His original research was in cardiac enzymology which led to the development of the MBCK test which was the standard diagnostic assay for myocardial infarction for more than 3 decades. In the late 1970s, his research interests switched to molecular biology and the genetics of cardiomyopathies. He is regarded as one of the founders of molecular cardiology and has identified and sequenced more than 20 genes responsible for cardiovascular disorders. In the past 6 years, he has pursued genome-wide association studies to identify genes predisposing to coronary artery disease (CAD) and myocardial infarction. The first genetic variant for CAD, 9p21, was identified by Dr. Robert’s laboratory and, in collaboration with the international consortium, CARDIoGRAM, has identified 13 novel genes for CAD.

Keywords: Molecular biology; Genetics; Heart disease; Genome wide association studies; Genetic linkage; Creatine kinase