Teaima T, Carlini GB, Gajjar RA, Aziz I, Shoura SJ, Shilbayeh AR, Battikh N, Alyousef T. Rates, predictors, and causes of readmission after transcatheter aortic valve replacement in patients with chronic kidney disease. World J Cardiol 2024; 16(7): 402-411 [PMID: 39086887 DOI: 10.4330/wjc.v16.i7.402]
Corresponding Author of This Article
Tareq Alyousef, MD, Staff Physician, Department of Cardiology, John H. Stroger, Jr. Hospital of Cook County, 1969 W Ogden Ave, Chicago, IL 60612, United States. talyousef@cookcountyhhs.org
Research Domain of This Article
Cardiac & Cardiovascular Systems
Article-Type of This Article
Retrospective Cohort Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Cardiol. Jul 26, 2024; 16(7): 402-411 Published online Jul 26, 2024. doi: 10.4330/wjc.v16.i7.402
Rates, predictors, and causes of readmission after transcatheter aortic valve replacement in patients with chronic kidney disease
Taha Teaima, Gianfranco Bittar Carlini, Rohan A Gajjar, Imran Aziz, Sami J Shoura, Abdul-Rahim Shilbayeh, Naim Battikh, Tareq Alyousef
Taha Teaima, Gianfranco Bittar Carlini, Rohan A Gajjar, Imran Aziz, Sami J Shoura, Abdul-Rahim Shilbayeh, Naim Battikh, Tareq Alyousef, Division of Cardiology, Department of Medicine, John H. Stroger, Jr. Hospital of Cook County, Chicago, IL 60612, United States
Author contributions: Teaima T and Alyousef T conceptualized the research idea and designed the study; Teaima T curated data from database and performed statistical anylysis, Gajjar RA contributed with data analysis; Teaima T, Carlini GB, Gajjar RA, Aziz I, Shoura SJ wrote the original manuscript draft; Shilbayeh AR and Battikh N contributed with manuscript review and further editing; Teaima T and Alyousef T supervised all the tasks. All authors have read and approve the final manuscript.
Institutional review board statement: This manuscript is exempt from Institutional Review Board approval, as national readmission database is a de-identified national administrative database and is readily available online at https://www.hcup-us.ahrq.gov.
Informed consent statement: National readmission database is a de-identified national administrative database and is readily available online no informed consent was required.
Conflict-of-interest statement: We have no financial relationships to disclose.
Data sharing statement: National readmission database is a de-identified national administrative database and is readily available online at https://www.hcup-us.ahrq.gov.
STROBE statement: The authors have read the STROBE Statement-checklist of items, and the manuscript was prepared and revised according to the STROBE Statement-checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Tareq Alyousef, MD, Staff Physician, Department of Cardiology, John H. Stroger, Jr. Hospital of Cook County, 1969 W Ogden Ave, Chicago, IL 60612, United States. talyousef@cookcountyhhs.org
Received: February 13, 2024 Revised: May 9, 2024 Accepted: June 6, 2024 Published online: July 26, 2024 Processing time: 161 Days and 19.5 Hours
Abstract
BACKGROUND
Transcatheter aortic valve replacement (TAVR) is a revolutionary procedure for severe aortic stenosis. The coexistence of chronic kidney disease (CKD) and TAVR introduces a challenge that significantly impacts patient outcomes.
AIM
To define readmission rates, predictors, and causes after TAVR procedure in CKD stage 1-4 patients.
METHODS
We used the national readmission database 2018 and 2020 to look into readmission rates, causes and predictors after TAVR procedure in patients with CKD stage 1-4.
RESULTS
Out of 24758 who underwent TAVR and had CKD, 7892 (32.4%) patients were readmitted within 90 days, and had higher adjusted odds of being females (adjusted odds ratio: 1.17, 95%CI: 1.02-1.31, P = 0.02) with longer length of hospital stay > 6 days, and more comorbidities including but not limited to diabetes mellitus, anemia, and congestive heart failure (CHF).
CONCLUSION
Most common causes of readmission included CHF (18.0%), sepsis, and complete atrioventricular block. Controlling readmission predictors with very close follow-up is warranted to prevent such high rate of readmission.
Core Tip: Our analysis of national readmission database for year 2018 to 2020 for 90 days readmissions for patients with chronic kidney disease stage 1-4 undergoing transcatheter aortic valve replacement showed considerably higher readmission rate to 32.4%. Majority were females and had higher comorbidity burden. Most common cause of 90 days readmission was congestive heart failure. Hence, we recommend optimization of co-morbidities and close follow up after index admission to prevent high rate of readmissions.
