Published online Oct 26, 2023. doi: 10.4330/wjc.v15.i10.479
Peer-review started: July 15, 2023
First decision: August 31, 2023
Revised: September 9, 2023
Accepted: September 28, 2023
Article in press: September 28, 2023
Published online: October 26, 2023
Processing time: 101 Days and 1.1 Hours
Despite the high prevalence of straight back syndrome (SBS), there is still limited research on this condition, posing challenges for effective diagnosis and treatment. The disease has been known for a long time, but there have been few related studies, which mostly consist of case reports. These studies have not been systematically summarized, making it difficult to meet the current needs of diagnosis and treatment. This article summarized the existing literature and comprehensively reviewed the diagnosis, pathogenesis, treatment, and research status of mitral valve prolapse related to SBS. We specifically emphasized the mechanisms and prognosis of SBS combined with mitral valve prolapse and discussed the latest research progress in this disease.
Core Tip: Straight back syndrome (SBS), a benign skeletal abnormality of the thorax, is typically accompanied by mitral valve prolapse. Despite its prevalence, there is limited research on this condition, making effective diagnosis and treatment challenging. Recent studies have revealed controversy on SBS and its related mechanisms. This review focused on the mechanisms and current research progress of SBS associated with mitral valve prolapse.