Regulation of MYC gene expression by aberrant Wnt/&beta;-catenin signaling in colorectal cancer

doi:10.4331/wjbc.v6.i4.290

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World Journal of Biological Chemistry

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1949-8454

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Biol Chem. Nov 26, 2015; 6(4): 290-300
Published online Nov 26, 2015. doi: 10.4331/wjbc.v6.i4.290

Table 1 MYC Wnt responsive DNA element chromosomal locations

MYC WRE	Chromosomal position	Distance to MYC TSS	Ref.
MYC 5’ WREs	chr8: 128747425	889-bp upstream	[14,28]
MYC 3’ WRE	chr8: 128755419	7105-bp downstream	[26,27,31]
Myc 3’ WRE	chr15: 61992066	6725-bp downstream	[32,33]
MYC -335 WRE	chr8: 128413279	335036-bp upstream	[46-51,55,56]
Myc -335 WRE	chr15: 61450712	534630-bp upstream	[52]
MYC -520 WRE	chr8: 128227619	520696-bp upstream	[59,61]
MYC -517 WRE	chr8: 128231269	517046-bp upstream	[59]
MYC -513 WRE	chr8: 128235209	513106-bp upstream	[59,61]
MYC -488 WRE	chr8: 128259779	488536-bp upstream	[59,61]
MYC -470 WRE	chr8: 128278129	470186-bp upstream	[59,61]
MYC super-enhancer	chr8: 128275000	473314-bp upstream	[61,69]

TSS: Transcription start site; WRE: Wnt responsive DNA element.

Citation: Rennoll S, Yochum G. Regulation of MYC gene expression by aberrant Wnt/β-catenin signaling in colorectal cancer. World J Biol Chem 2015; 6(4): 290-300
URL: https://www.wjgnet.com/1949-8454/full/v6/i4/290.htm
DOI: https://dx.doi.org/10.4331/wjbc.v6.i4.290