FoxO3a and disease progression

doi:10.4331/wjbc.v5.i3.346

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World Journal of Biological Chemistry

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1949-8454

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Biol Chem. Aug 26, 2014; 5(3): 346-354
Published online Aug 26, 2014. doi: 10.4331/wjbc.v5.i3.346

Table 1 FoxO3a target genes in various cell types

FoxO3a target genes	Cell types
Bim	Neuron cells[48]
TRAIL	Bcr/Abl transformed cells[57]
TRAIL	Chronic myeloid leukemia[46]
PUMA	Lymphoid cells[58]
Noxa	Neuroblastoma[59]
FasL	Glomerular mesangial cells[102]
p27, Caveolin-1	Glomerular mesangial cells[102]
p21	Glomerular mesangial cells[102]

Shown are previously known FoxO3a target genes that regulate cell proliferation and apoptosis in different cell types.

Citation: Nho RS, Hergert P. FoxO3a and disease progression. World J Biol Chem 2014; 5(3): 346-354
URL: https://www.wjgnet.com/1949-8454/full/v5/i3/346.htm
DOI: https://dx.doi.org/10.4331/wjbc.v5.i3.346