Neonatal gastric perforation: A single center experience

Table 1 Patient characteristics

Patient	Gender	Date of birth	GA (wk)	Term	BW (g)	Delivery	Symptom onset (d)	Time from symptoms to surgery (d)	pH	NG tube
A	F	1983-02-24	40+2	Full term	3500	Natural	5	1	N.D.	Yes
B	F	1987-07-09	40	Full term	2950	Natural	2	2	7.13	Yes
C	M	1990-09-05	35	Preterm	2190	Natural	2	2	7.03	Yes
D	M	1993-06-03	38+4	Full term	2950	C-sec	4	0	7.19	No
E	M	1999-05-13	36+3	Full term	2860	Natural	2	0	7.43	No
F	F	2003-05-10	32+6	Preterm	1960	C-sec	2	0	N.D.	Yes
G	M	2009-02-03	38	Full term	3620	Natural	0	1	7.086	Yes
H	M	2011-08-03	24	Preterm	730	Natural	4	1	7.058	Yes
I	F	2011-12-27	39+3	Full term	4040	Natural	2	0	7.391	Yes

GA: Gestational age; BW: Birth weight; F: Female; M: Male; NG: Nasogastric; C-sec: Cesarean section.

Table 2 Preoperative conditions

Initial symptom	Diet	Ventilator	O2 therapy	Pneumoperitoneum on X-ray	Associated anomaly	Maternal problem
High fever, vomiting, dyspnea	Yes	Yes	Yes	No	Diaphragmatic eventration	None
Vomiting dyspnea	Yes	Yes	Yes	No	Diaphragmatic eventration	None
Hematemesis	Yes	No	Yes	No		PROM
Abd. dist, vomiting, fever	Yes	No	No	Yes		None
Abd. dist	Yes	No	No	Yes		None
Abd. dist	No	No	No	Yes	TEF	None
Abd. dist	No	Yes	Yes	Yes	CDH	None
Metabolic acidosis, abd. dist,	No	Yes	Yes	Yes	Antral web	PROM
Abd. dist	Yes	No	No	Yes		None

PROM: Premature rupture of membranes.

Table 3 Intraoperative and postoperative outcomes

Patient	Surgical procedure	Perforated site	Length (cm)	NEC	Complications	Hospital stay (d)	Survival
A	RA	Body, LC, PW	4	Yes	Wound problem	18	Alive
B	RA	Body, PW	2.5	No	Sepsis	4	Deceased
C	Primary repair	Whole, GC	10	Yes	Sepsis	46	Deceased
D	Primary repair	Whole, GC	10	No		11	Alive
E	RA	Body, GC	5	Yes		28	Alive
F	Primary repair	LC	3	No		40	Alive
G	Primary repair	Body, GC	1	No		24	Alive
H	Primary repair	(1) LC (2) body, AW	5	No		131	Alive
I	Primary repair	Antrum, AW	0.5	No	Wound problem	11	Alive

NEC: Necrotizing enterocolitis; RA: Resection and anastomosis; LC: Lesser curvature; PW: Posterior wall; GC: Greater curvature; AW: Anterior wall.

Table 4 Prognostic factor analysis

	Survival (n = 7)	Deceased (n = 2)	P-value
Male	4	1	1.000
Birth before 1990	1	2	0.083
Birth before 2000	3	2	0.444
Preterm	2	1	1.000
BW < 2500 g	2	1	1.000
pH < 7.30	3	2	1.000
NG tube	5	2	1.000
Diet	4	2	0.500
Ventilator	3	1	1.000
O2 therapy	3	2	0.464
Pneumoperitoneum	6	0	0.083
Associated anomaly	5	1	1.000
Time from symptom onset to surgery > 24 h	0	2	< 0.001
Length > 2 cm	5	2	1.000
Primary repair	5	1	1.000
NEC	2	1	1.000

BW: Body weight; NG: Nasogastric; NEC: Necrotizing enterocolitis.