Brief Article
Copyright ©2013 Baishideng Publishing Group Co.
World J Gastrointest Surg. Apr 27, 2013; 5(4): 104-109
Published online Apr 27, 2013. doi: 10.4240/wjgs.v5.i4.104
Table 1 Estimates and scores used for creation of the clinical score
SymptomOdds ratioPoints
Pain1.21
Diarrhea1.21
Constipation0.91-1
Vomiting1.32
Weight loss1.11
Rectal bleeding0.65-3
Melena2.55
Change in BH1.11
Legend
0.5-0.7-3
0.7-0.9-2
0.9-1.0-1
1.0-1.21
1.2-1.42
1.4-1.63
1.6-1.84
>1.85
Table 2 Distribution of symptoms among patients, divided according to the Union for International Cancer Control TNM staging system n (%)
StageAbdominal painDiarrheaConstipationVomitWeight lossRectal bleedingMelenaChange in BH1
110 (30.3)3 (9.0)11 (33.3)1 (3.0)11 (33.3)8 (24.2)1 (3.0)11 (33.3)
2a44 (62.8)11 (15.7)20 (28.6)11 (15.7)22 (31.4)11 (15.7)2 (2.8)34 (48.6)
2b2 (66.6)0 (0.0)0 (0.0)1 (33.3)0 (0.0)0 (0.0)0 (0.0)0 (0.0)
3a5 (45.4)1 (9.0)2 (18.2)1 (9.0)3 (27.3)0 (0.0)0 (0.0)1 (9.0)
3b15 (44.1)3 (8.8)8 (23.5)3 (2.9)6 (17.6)5 (14.7)1 (2.9)10 (29.4)
3c10 (37.0)1 (3.7)10 (37.0)3 (11.1)7 (25.9)10 (37)0 (0.0)15 (55.5)
435 (60.3)7 (12.1)18 (31.3)7 (12.1)28 (48.3)13 (22.4)3 (5.2)27 (46.5)
Total121 (51.3)26 (11)69 (29.2)27 (11.4)77 (32.6)47 (19.9)7 (2.9)98 (41.5)
P value0.010.780.790.350.040.140.950.03
Table 3 Comparison of symptoms with respect to tumor location n (%)
SymptomLeft colon n = 139Right colon n = 97P value
Pain73 (52.5)48 (49.5)0.7
Diarrhea12 (8.6)14 (14.4)0.2
Constipation47 (33.8)22 (22.7)0.08
Vomiting16 (11.5)11 (11.3)1
Weight loss48 (34.5)29 (29.9)0.48
Rectal bleeding37 (26.6)10 (10.3)0.002
Melena5 (3.6)2 (2.1)0.71
Change in BH68 (48.9)30 (30.9)0.006
Table 4 Crude univariate analysis comparing the presentation of symptoms among survivors and non-survivors n (%)
SymptomSurvivors n = 142Non-survivors n = 93Univariate P valueMultivariate P valueOR (95%CI)
Pain66 (46.2)55 (59.1)0.050.381.4 (0.7-2.8)
Diarrhea13 (9.1)13 (14)0.240.511.5 (0.4-5.6)
Constipation41 (28.7)28 (30.1)0.810.910.94 (0.3-2.7)
Vomiting12 (8.4)15 (16.1)0.070.241.9 (0.6-5.6)
Weight loss43 (30)34 (36.6)0.320.630.8 (0.4-1.7)
Rectal bleeding34 (23.8)13 (14)0.060.0040.25 (0.1-0.7)
Melena2 (1.4)5 (5.4)0.10.047.4 (1.1-72.7)
Change in BH56 (39.2)42 (45.2)0.360.961 (0.4-2.9)
Table 5 Clinical score predicts mortality independently of age, stage and the duration of complaints
MortalityOR (95%CI)
Clinical score > 10.0013.1 (1.5-6.1)
Age0.0030.96 (0.94-0.99)
Stage< 0.00135 (5.3-703.7)
Duration of complaints0.050.6 (0.26-1.0)