Effects of fluid therapy combined with a preoperative glucose load regimen on postoperative recovery in patients with rectal cancer

Table 1 Comparison of operative conditions, mean ± SD

Group	Number of cases	Operation time (minute)	Intraoperative bleeding volume (mL)	Crystalloid liquid (mL)	Colloid fluid (mL)	Total infusion volume (mL)	Urine volume (mL)
Observation group	92	183.61 ± 8.52	249.25 ± 10.22	1134.69 ± 20.98	521.06 ± 10.52	1908.25 ± 20.66	321.58 ± 10.52
Control group	92	183.67 ± 8.55	248.63 ± 10.36	1129.87 ± 20.55	532.05 ± 10.56	1915.58 ± 20.32	522.14 ± 10.777
t value		0.048	0.409	1.574	7.072	2.426	127.733
P value		0.962	0.683	0.117	< 0.001	0.016	< 0.001

Table 2 Comparison of blood lactic acid levels, mean ± SD

Group	Number of cases	Blood lactic acid level (mmol/L)
		Immediately after entering operating room	Immediately after surgery
Observation group	92	1.09 ± 0.22	1.24 ± 0.24
Control group	92	1.10 ± 0.25	1.38 ± 0.29
t value		0.288	3.567
P value		0.774	< 0.001

Table 3 Comparison of postoperative recovery, mean ± SD

Group	Number of cases	Time to first exhaust (h)	Time to tracheal extubation (h)	Time to food intake (h)	Postoperative hospital stay (d)
Observation group	92	72.63 ± 6.88	0.66 ± 0.16	67.58 ± 4.28	11.14 ± 1.22
Control group	92	90.51 ± 6.40	0.69 ± 0.17	77.25 ± 4.63	14.78 ± 1.40
t value		18.251	1.233	14.710	18.801
P value		< 0.001	0.219	< 0.001	< 0.001

Table 4 Comparison of cognitive condition (mean ± SD, points)

Group	Number of cases	Mini-Mental State Examination score
		Preoperatively	3 d after surgery
Observation group	92	27.42 ± 1.05	26.77 ± 1.15
Control group	92	27.33 ± 1.11	25.01 ± 1.25
t value		0.565	9.939
P value		0.573	< 0.001

Table 5 Comparison of hemodynamic indicators, mean ± SD

Group	Number of cases	HR (times/min)					Mean arterial pressure (mmHg)					Pulse pressure variability (%)
		T0	T1	T2	T3	T4	T0	T1	T2	T3	T4	T0	T1	T2	T3	T4
Observation group	92	66.41 ± 4.55	67.25 ± 5.66	68.69 ± 4.60	68.99 ± 4.05	70.11 ± 4.05	76.02 ± 4.05	78.10 ± 6.25	80.01 ± 6.11	81.98 ± 6.40	83.99 ± 6.24	-	11.75 ± 1.02	9.87 ± 0.98	12.79 ± 1.13	8.82 ± 0.76
Control group	92	66.78 ± 4.25	67.05 ± 5.14	68.25 ± 4.05	68.11 ± 4.14	70.25 ± 4.22	76.27 ± 5.60	77.89 ± 6.11	80.25 ± 6.45	82.66 ± 6.52	84.14 ± 6.66	-	12.01 ± 1.25	9.89 ± 0.94	14.96 ± 1.35	9.02 ± 0.77
t value		0.570	0.251	0.689	1.457	0.230	0.347	0.230	0.259	0.714	0.158		1.546	0.141	11.823	1.773
P value		0.569	0.802	0.492	0.147	0.819	0.729	0.818	0.796	0.476	0.875		0.124	0.888	< 0.001	0.078

Table 6 Comparison of inflammatory factor levels, mean ± SD

Group	Number of cases	TNF-α (mg/L)		IL-6 (ng/L)
		Preoperatively	3 d after surgery	Preoperative	3 d after surgery
Observation group	92	60.14 ± 4.03	32.53 ± 3.06	80.25 ± 8.79	41.26 ± 4.03
Control group	92	60.22 ± 4.14	38.77 ± 3.14	80.36 ± 8.41	52.06 ± 4.19
t value		0.133	13.651	0.087	17.819
P value		0.894	< 0.001	0.931	< 0.001

Table 7 Comparison of oxygen metabolism in brain tissue, mean ± SD

Group	Number of cases	Left rScO2 (%)			Right rScO2 (%)
		T1	T2	T3	T1	T2	T3
Observation group	92	72.05 ± 6.25	68.41 ± 5.05	66.10 ± 6.31	70.22 ± 6.37	67.08 ± 5.40	65.11 ± 4.06
Control group	92	72.11 ± 6.45	64.25 ± 5.11	62.08 ± 6.16	70.40 ± 6.49	64.99 ± 5.19	61.78 ± 4.27
t value		0.064	5.554	4.373	0.190	2.677	5.421
P value		0.949	< 0.001	< 0.001	0.850	0.008	< 0.001

Table 8 Comparison of incidence of complications, n (%)

Group	Number of cases	Nausea and vomiting	Wound infection	Pulmonary infection	Urinary system infection	Total incidence
Observation group	92	1 (1.09)	1 (1.09)	0	0	2 (2.17)
Control group	92	2 (2.17)	3 (3.26)	0	0	5 (5.43)
χ2						0.594
P value						0.441