Randomized Controlled Trial
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Aug 27, 2024; 16(8): 2662-2670
Published online Aug 27, 2024. doi: 10.4240/wjgs.v16.i8.2662
Effects of fluid therapy combined with a preoperative glucose load regimen on postoperative recovery in patients with rectal cancer
Lv-Chi Xia, Ke Zhang, Chuan-Wen Wang
Lv-Chi Xia, Ke Zhang, Chuan-Wen Wang, Department of Emergency Medicine, Jiujiang First People's Hospital, Jiujiang 332000, Jiangxi Province, China
Author contributions: Xia LC designed the research study; Xia LC, Zhang K, and Wang CW performed the primary literature and data extraction; Xia LC, Zhang K, and Wang CW analyzed the data and wrote the manuscript; Xia LC was responsible for revising the manuscript for important intellectual content; all authors read and approved the final version.
Institutional review board statement: The study was reviewed and approved by the Science and Research Office of the Jiujiang Municipal First People's Hospital.
Clinical trial registration statement: The study was registered at the Clinical Trial Center with registration number: Researchregistry10373.
Informed consent statement: All study participants or their legal guardians provided informed written consent before enrollment.
Conflict-of-interest statement: There are no conflicts of interest to report.
Data sharing statement: No additional data are available.
CONSORT 2010 statement: The authors have read the CONSORT 2010 Statement, and the manuscript was prepared and revised according to the CONSORT 2010 Statement.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ke Zhang, MMed, Attending Doctor, Department of Emergency Medicine, Jiujiang First People's Hospital, No. 48 Taling South Road, Xunyang District, Jiujiang 332000, Jiangxi Province, China. zk18720166866@126.com
Received: May 7, 2024
Revised: June 8, 2024
Accepted: July 1, 2024
Published online: August 27, 2024
Processing time: 101 Days and 3.9 Hours
Core Tip

Core Tip: The application of goal-directed fluid therapy combined with a preoperative glucose load regimen in patients with rectal cancer undergoing radical resection can not only significantly improve the postoperative recovery and brain tissue oxygen metabolism, but also alleviate inflammatory reactions, and improve cognitive function, hemodynamics, and blood lactate levels. This study observed the postoperative recovery of patients undergoing radical resection for rectal cancer, and confirmed the effectiveness of goal-directed fluid therapy combined with a preoperative glucose load regimen in patients undergoing radical resection for rectal cancer.