Influencing factors and risk prediction model for emergence agitation after general anesthesia for primary liver cancer

Table 1 Comparison of general information between the two groups, n (%)

Factor	EA group (n = 51)	Non-EA group (n = 149)	χ2/t	P value
Gender
Female	22 (43.14)	67 (44.97)	0.051	0.821
Male	29 (56.86)	82 (55.03)
Age (years)	55.67 ± 7.46	50.23 ± 6.15	-5.145	< 0.001
Smoking history
No	24 (47.06)	76 (51.01)	0.237	0.626
Yes	27 (52.94)	73 (48.99)
Drinking history
No	25 (49.02)	85 (57.05)	0.989	0.320
Yes	26 (50.98)	64 (42.95)
Hypertension
No	32 (62.75)	106 (71.14)	1.252	0.263
Yes	19 (37.25)	43 (28.86)
Diabetes
No	34 (66.67)	109 (73.15)	0.785	0.376
Yes	17 (33.33)	40 (26.85)
ASA grade
I	11 (21.57)	70 (46.98)	21.096	< 0.001
II	18 (35.29)	58 (38.93)
III	22 (43.14)	21 (14.09)
Indwelling catheter
No	18 (35.29)	104 (69.80)	19.014	< 0.001
Yes	33 (64.71)	45 (30.20)
Postoperative analgesia
No	33 (64.71)	55 (36.91)	11.911	0.001
Yes	18 (35.29)	94 (63.09)
Operation time (minute)	302.76 ± 65.51	264.38 ± 61.81	-3.770	< 0.001
Anesthesia time (minute)	348.14 ± 65.09	313.48 ± 62.24	-3.392	< 0.001
Awakening time (minute)	42.62 ± 3.58	41.91 ± 3.87	-1.129	0.260
Postoperative pain (scores)	4.43 ± 1.20	2.60 ± 0.76	-10.201	< 0.001

EA: Emergence agitation; ASA: American Society of Anesthesiologists.

Table 2 Assignment table of factors affecting emergence agitation in patients after general anesthesia

Factor	Assign
Age	Original input
Operation time	Original input
Anesthesia time	Original input
ASA grade	0 = I, 1 = II, 2 = III
Indwelling catheter	0 = No, 1 = Yes
Postoperative analgesia	0 = No, 1 = Yes
Postoperative pain	Original input

ASA: American Society of Anesthesiologists.

Table 3 Logistic regression analysis of emergence agitation-related factors

Factor	B	SE	Wald	P value	OR value (95%CI)
Age	0.202	0.065	9.693	0.002	1.224 (1.078-1.391)
Operation time (minute)	0.010	0.006	3.065	0.080	1.011 (0.999-1.022)
Anesthesia time (minute)	-0.003	0.005	0.259	0.611	0.997 (0.987-1.008)
ASA grade (Class I as reference)	-	-	6.180	0.045	-
II	0.076	0.813	0.009	0.925	1.079 (0.219-5.309)
III	2.165	0.937	5.338	0.021	8.713 (1.389-54.671)
Indwelling catheter	1.529	0.730	4.388	0.036	4.613 (1.103-19.290)
Postoperative analgesia	-3.516	1.009	12.145	< 0.001	0.030 (0.004-0.215)
Postoperative pain	4.144	0.989	17.543	< 0.001	63.079 (9.070-438.679)

SE: Standard error; OR: Odds ratio; CI: Confidence interval; ASA: American Society of Anesthesiologists.