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©The Author(s) 2024.
World J Gastrointest Surg. Jul 27, 2024; 16(7): 2145-2156
Published online Jul 27, 2024. doi: 10.4240/wjgs.v16.i7.2145
Published online Jul 27, 2024. doi: 10.4240/wjgs.v16.i7.2145
Table 1 Univariate analysis of postoperative death in patients with colorectal cancer, n (%)
Data | Death group (n = 23) | Survival group (n = 65) | χ2 | P value | |
Gender | Male | 14 (60.87) | 37 (56.92) | 0.109 | 0.742 |
Female | 9 (39.13) | 28 (43.08) | |||
Age | ≥ 60 years | 15 (65.22) | 36 (55.38) | 0.674 | 0.412 |
< 60 years | 8 (34.78) | 29 (44.62) | |||
BMI | < 18.5 kg/m2 | 0 (0.00) | 4 (6.15) | 16.992 | < 0.001 |
18.5-24 kg/m2 | 11 (47.83) | 55 (84.62) | |||
> 24 kg/m2 | 12 (52.17) | 6 (9.23) | |||
Smoking history | Yes | 9 (39.13) | 23 (35.38) | 0.103 | 0.748 |
No | 14 (60.87) | 42 (64.62) | |||
Drinking history | Yes | 7 (30.43) | 18 (27.69) | 0.063 | 0.802 |
No | 16 (69.57) | 47 (72.31) | |||
Pathological stage | I | 0 (0.00) | 10 (15.38) | 15.401 | 0.001 |
II | 7 (30.43) | 39 (60.00) | |||
III | 12 (52.17) | 13 (20.00) | |||
IV | 4 (17.39) | 3 (4.62) | |||
Blood vessel invasion | Yes | 1 (4.35) | 2 (3.08) | < 0.001 | > 0.999 |
No | 22 (95.65) | 63 (96.92) | |||
Degree of tumor differentiation | Poorly differentiated | 6 (26.09) | 5 (7.69) | 8.950 | 0.011 |
Moderately differentiated | 16 (69.57) | 42 (64.62) | |||
Highly differentiated | 1 (4.35) | 18 (27.69) | |||
Lymphatic metastasis | Yes | 10 (43.48) | 14 (21.54) | 4.123 | 0.042 |
No | 13 (56.52) | 51 (78.46) | |||
Tumor site | Right semicolon | 8 (34.78) | 12 (18.46) | 2.824 | 0.244 |
Left semicolon | 5 (21.74) | 14 (21.54) | |||
Rectum | 10 (43.48) | 39 (60.00) | |||
Intestinal wall thickening form | Polyps or cauliflower thickening | 6 (26.09) | 9 (13.85) | 2.201 | 0.532 |
Eccentric thickening | 9 (39.13) | 28 (43.08) | |||
Uneven ring thickening | 6 (26.09) | 24 (36.92) | |||
Uniform ring thickening | 2 (8.70) | 4 (6.15) | |||
Degree of periintestinal infiltration | Mild | 0 (0.00) | 33 (50.77) | 48.385 | < 0.001 |
Moderate | 4 (17.39) | 27 (41.54) | |||
Severe | 19 (82.61) | 5 (7.69) | |||
Transformation rate of signal | Mild | 8 (34.78) | 22 (33.85) | 2.879 | 0.237 |
Moderate | 6 (26.09) | 28 (43.08) | |||
Severe | 9 (39.13) | 15 (23.08) | |||
Low-density area after enhancement | Yes | 13 (56.52) | 40 (61.54) | 0.178 | 0.673 |
No | 10 (43.48) | 25 (38.46) | |||
Lymph node location | Mesenterium | 15 (65.22) | 36 (55.38) | 1.234 | 0.540 |
Root | 7 (30.43) | 22 (33.85) | |||
Lateral | 1 (4.35) | 7 (10.77) | |||
Tumor size | < 4 cm | 4 (17.39) | 38 (58.46) | 11.486 | 0.001 |
≥ 4 cm | 19 (82.61) | 27 (41.54) | |||
Lymph node CT value | < 30 HU | 4 (17.39) | 39 (60.00) | 10.697 | 0.001 |
≥ 30 HU | 19 (82.61) | 26 (40.00) | |||
Mean tumor long-axis diameter | < 0.6 cm | 4 (17.39) | 35 (53.85) | 7.731 | 0.005 |
≥ 0.6 cm | 19 (82.61) | 30 (46.15) | |||
Mean tumor short-axis diameter | < 0.45 cm | 5 (21.74) | 36 (55.38) | 7.729 | 0.005 |
≥ 0.45 cm | 18 (78.26) | 29 (44.62) |
Table 2 Assignment table
Independent variable | Assignment |
BMI | 0: < 18.5 kg/m2; 1: 18.5-24 kg/m2; 2: > 24 kg/m2 |
Pathological stage | 1: I; 2: II; 3: III; 4: IV |
Degree of tumor differentiation | 1: Poorly differentiated; 2: Moderately differentiated; 3: Highly differentiated |
Degree of periintestinal infiltration | 1: Mild; 2: Moderate; 3: Severe |
Tumor size | 0: < 4 cm; 1: ≥ 4 cm |
Lymph node CT value | 0: < 30 HU; 1: ≥ 30 HU |
Mean tumor long-axis diameter | 0: < 0.6 cm; 1: ≥ 0.6 cm |
Mean tumor short-axis diameter | 0: < 0.45 cm; 1: ≥ 0.45 cm |
Table 3 Multivariate Cox regression analysis of postoperative death in patients with colorectal cancer
Independent variable | B | SE | Wald | P value | OR | 95%CI |
BMI | 0.409 | 0.139 | 8.621 | 0.003 | 1.506 | 1.146-1.979 |
Pathological stage | 2.255 | 0.521 | ||||
I | -7.741 | 222.369 | 0.001 | 0.972 | 0.000 | 0.000-8.303 |
II | 0.957 | 0.780 | 1.504 | 0.220 | 2.603 | 0.564-12.003 |
III | 1.052 | 0.712 | 2.183 | 0.140 | 2.865 | 0.709-11.569 |
Degree of tumor differentiation | 1.749 | 0.417 | ||||
Poorly differentiated | 0.686 | 1.290 | 0.283 | 0.595 | 1.986 | 0.158-24.909 |
Moderately differentiated | -0.302 | 1.114 | 0.074 | 0.786 | 0.739 | 0.083-6.565 |
Degree of periintestinal infiltration | 7.030 | 0.030 | ||||
Mild | -12.450 | 167.468 | 0.006 | 0.941 | 0.000 | 0.000-1.390 |
Moderate | -1.784 | 0.673 | 7.025 | 0.008 | 0.168 | 0.045-0.628 |
Tumor size | 1.522 | 0.660 | 5.322 | 0.021 | 4.581 | 1.257-16.691 |
Lymph node CT value | 1.362 | 0.689 | 3.911 | 0.048 | 3.904 | 1.012-15.059 |
Mean tumor long-axis diameter | 0.918 | 0.809 | 1.287 | 0.257 | 2.505 | 0.513-12.240 |
Table 4 Receiver operating characteristic analysis
Variable | Area (95%CI) | Standard error | P value | Sensitivity | Specificity |
BMI | 0.847 (0.753-0.942) | 0.048 | < 0.001 | 82.6% | 83.1% |
Degree of periintestinal infiltration | 0.735 (0.613-0.857) | 0.062 | 0.001 | 52.2% | 86.2% |
Tumor size | 0.705 (0.587-0.824) | 0.06 | 0.004 | 82.6% | 58.5% |
Lymph node CT value | 0.648 (0.518-0.778) | 0.066 | 0.036 | 69.6% | 60.0% |
Table 5 Correlation between postoperative survival time and abdominal computed tomography signs in patients with colorectal cancer
Independent variable | Survival time | BMI | Degree of periintestinal infiltration | Tumor size | Lymph nodes CT value | Mean tumor long-axis diameter | Mean tumor short-axis diameter | |
Survival time | r value | - | -0.559 | -0.679 | -0.430 | -0.585 | -0.425 | -0.385 |
P value | - | < 0.001 | < 0.001 | < 0.001 | < 0.001 | < 0.001 | < 0.001 | |
BMI | r value | - | - | 0.303 | 0.254 | 0.431 | 0.211 | 0.437 |
P value | - | - | 0.004 | 0.017 | < 0.001 | 0.049 | < 0.001 | |
Degree of periintestinal infiltration | r value | - | - | - | 0.199 | 0.246 | 0.332 | 0.264 |
P value | - | - | - | 0.063 | 0.021 | 0.002 | 0.013 | |
Tumor size | r value | - | - | - | - | 0.352 | 0.303 | 0.276 |
P value | - | - | - | - | 0.001 | 0.004 | 0.009 | |
Lymph node CT value | r value | - | - | - | - | - | 0.390 | 0.420 |
P value | - | - | - | - | - | < 0.001 | < 0.001 | |
Mean tumor long-axis diameter | r value | - | - | - | - | - | - | 0.587 |
P value | - | - | - | - | - | - | < 0.001 | |
Mean tumor short-axis diameter | r value | - | - | - | - | - | - | - |
P value | - | - | - | - | - | - | - |
- Citation: Yang SM, Liu JM, Wen RP, Qian YD, He JB, Sun JS. Correlation between abdominal computed tomography signs and postoperative prognosis for patients with colorectal cancer. World J Gastrointest Surg 2024; 16(7): 2145-2156
- URL: https://www.wjgnet.com/1948-9366/full/v16/i7/2145.htm
- DOI: https://dx.doi.org/10.4240/wjgs.v16.i7.2145