Retrospective Study
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Jul 27, 2024; 16(7): 2145-2156
Published online Jul 27, 2024. doi: 10.4240/wjgs.v16.i7.2145
Correlation between abdominal computed tomography signs and postoperative prognosis for patients with colorectal cancer
Shao-Min Yang, Jie-Mei Liu, Rui-Ping Wen, Yu-Dong Qian, Jing-Bo He, Jing-Song Sun
Shao-Min Yang, Department of Radiology, Xingtan Hospital Affiliated to Shunde Hospital of Southern Medical University, Foshan 528315, Guangdong Province, China
Jie-Mei Liu, Department of Rehabilitation Medicine, Shunde Hospital, Southern Medical University, Foshan 528399, Guangdong Province, China
Rui-Ping Wen, Yu-Dong Qian, Jing-Song Sun, Department of Radiology, Lecong Hospital of Shunde, Foshan 528315, Guangdong Province, China
Jing-Bo He, Department of Ultrasound, Lecong Hospital of Shunde, Foshan 528315, Guangdong Province, China
Co-first authors: Shao-Min Yang and Jie-Mei Liu.
Co-corresponding authors: Jing-Bo He and Jing-Song Sun.
Author contributions: Yang SM and Liu JM contributed equally to this work, and they designed the manuscript; Wen RP and Qian YD organized the clinical data; He JB and Sun JS contributed equally to this work as the co-corresponding authors of this manuscript, and they analyzed the data, prepared the figures, and supervised this study.
Institutional review board statement: The study was reviewed and approved by the Xingtan Hospital Affiliated to Shunde Hospital of Southern Medical University Institutional Review Board.
Informed consent statement: The Institutional Review Board approved the exemption from informed consent.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: The data used in this study can be obtained from the corresponding author upon request.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jing-Bo He, MBBS, Attending Doctor, Department of Ultrasound, Lecong Hospital of Shunde, No. 45 Lecong Avenue, Lecong Town, Shunde District, Foshan 528315, Guangdong Province, China. bo1221sun@163.com
Received: April 3, 2024
Revised: May 8, 2024
Accepted: May 27, 2024
Published online: July 27, 2024
Processing time: 109 Days and 21.6 Hours
Abstract
BACKGROUND

Patients with different stages of colorectal cancer (CRC) exhibit different abdominal computed tomography (CT) signs. Therefore, the influence of CT signs on CRC prognosis must be determined.

AIM

To observe abdominal CT signs in patients with CRC and analyze the correlation between the CT signs and postoperative prognosis.

METHODS

The clinical history and CT imaging results of 88 patients with CRC who underwent radical surgery at Xingtan Hospital Affiliated to Shunde Hospital of Southern Medical University were retrospectively analyzed. Univariate and multivariate Cox regression analyses were used to explore the independent risk factors for postoperative death in patients with CRC. The three-year survival rate was analyzed using the Kaplan-Meier curve, and the correlation between postoperative survival time and abdominal CT signs in patients with CRC was analyzed using Spearman correlation analysis.

RESULTS

For patients with CRC, the three-year survival rate was 73.86%. The death group exhibited more severe characteristics than the survival group. A multivariate Cox regression model analysis showed that body mass index (BMI), degree of periintestinal infiltration, tumor size, and lymph node CT value were independent factors influencing postoperative death (P < 0.05 for all). Patients with characteristics typical to the death group had a low three-year survival rate (log-rank χ2 = 66.487, 11.346, 12.500, and 27.672, respectively, P < 0.05 for all). The survival time of CRC patients was negatively correlated with BMI, degree of periintestinal infiltration, tumor size, lymph node CT value, mean tumor long-axis diameter, and mean tumor short-axis diameter (r = -0.559, 0.679, -0.430, -0.585, -0.425, and -0.385, respectively, P < 0.05 for all). BMI was positively correlated with the degree of periintestinal invasion, lymph node CT value, and mean tumor short-axis diameter (r = 0.303, 0.431, and 0.437, respectively, P < 0.05 for all).

CONCLUSION

The degree of periintestinal infiltration, tumor size, and lymph node CT value are crucial for evaluating the prognosis of patients with CRC.

Keywords: Colorectal cancer; Abdominal; Computed tomography signs; Radical surgery; Prognosis; Correlation

Core Tip: The incidence and mortality rates of colorectal cancer (CRC) are alarming. We analyzed the demographic data, pathological information, and abdominal computed tomography (CT) findings of 88 patients with CRC after radical surgery. This is a retrospective single-center study to investigate the correlation of demographic data, pathological information, and abdominal CT signs with prognosis. We solved the problem of CRC prognosis assessment by observing the changes in the survival rate of patients with CRC under different influencing factors.